Anti-COL2A1 Antibody (CAB1560)

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SKU:
CAB1560
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

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抗体名:Anti-COL2A1 Antibody
抗体コード:CAB1560
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IHC
反応性:Human, Mouse,
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 873-1072 of human COL2A1 (NP_149162.2).
申し込み:WB IHC
推奨希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:200
反応性:Human, Mouse,
ポジティブサンプル:Mouse liver
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 873-1072 of human COL2A1 (NP_149162.2).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:GEPG LQGP AGPP GEKG EPGD DGPS GAEG PPGP QGLA GQRG IVGL PGQR GERG FPGL PGPS GEPG KQGA PGAS GDRG PPGP VGPP GLTG PAGE PGRE GSPG ADGP PGRD GAAG VKGD RGET GAVG APGA PGPP GSPG PAGP TGKQ GDRG EAGA QGPM GPSG PAGA RGIQ GPQG PRGD KGEA GEPG ERGL KGHR GFTG LQGL
遺伝子ID:1280
Uniprot:P02458
セルラーロケーション:Secreted, extracellular matrix, extracellular space
計算された分子量:29kDa/134kDa/141kDa
観察された分子量:141kDa
同義語:COL2A1, ANFH, AOM, COL11A3, SEDC, STL1
バックグラウンド:This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
UniProt Protein Function:Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
NCBI Summary:This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:P02458
NCBI GenInfo Identifier:124056489
NCBI Gene ID:1280
NCBI Accession:P02458.3
UniProt Secondary Accession:P02458,Q12985, Q14009, Q14044, Q14045, Q14046, Q14047 Q14056, Q14058, Q16672, Q1JQ82, A6NGA0,
UniProt Related Accession:P02458
Molecular Weight:134,389 Da
NCBI Full Name:Collagen alpha-1(II) chain
NCBI Synonym Full Names:collagen type II alpha 1 chain
NCBI Official Symbol:COL2A1  
NCBI Official Synonym Symbols:AOM; ANFH; SEDC; STL1; COL11A3  
NCBI Protein Information:collagen alpha-1(II) chain
UniProt Protein Name:Collagen alpha-1(II) chain
UniProt Synonym Protein Names:Alpha-1 type II collagenCurated
UniProt Gene Name:COL2A1  
Anti-COL2A1 Antibody (CAB1560)Western blot analysis of extracts of mouse liver, using COL2A1 antibody (CAB1560) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-COL2A1 Antibody (CAB1560)Immunohistochemistry of paraffin-embedded Human breast cancer using COL2A1 Rabbit pAb (CAB1560) at dilution of 1:100 (40x lens).
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