Anti-Coilin Antibody (CAB3483)
- SKU:
- CAB3483
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-Coilin Antibody |
| 抗体コード: | CAB3483 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human Coilin |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, Mouse lung |
| 免疫原: | A synthesized peptide derived from human Coilin |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 8161 |
| Uniprot: | P38432 |
| セルラーロケーション: | |
| 計算された分子量: | 80kDa |
| 観察された分子量: | 80KDa |
| 同義語: | CLN80, p80-coilin |
| バックグラウンド: | The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | coilin: an ubiquitous protein found in nuclear coiled bodies (CBS), nuclear suborganelles involved in the post-transcriptional modification of snRNPs and small nucleolar RNAs. snRNPs undergo 2'-O-methylation and pseudouridylation in CBS. Differential methylation and phosphorylation of coilin likely influences localization among nuclear bodies and the composition and assembly of CBS. Located in the interchromatin space between the nucleolus and the nucleus. |
| UniProt Protein Details: | Protein type:Oxidoreductase Chromosomal Location of Human Ortholog: 17q22 Cellular Component: nucleoplasm; Cajal body; membrane; cytoplasm; nucleolus; nucleus Molecular Function:protein C-terminus binding; identical protein binding; protein binding |
| NCBI Summary: | The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P38432 |
| NCBI GenInfo Identifier: | 585632 |
| NCBI Gene ID: | 8161 |
| NCBI Accession: | P38432.1 |
| UniProt Secondary Accession: | P38432,B2R931, |
| UniProt Related Accession: | P38432 |
| Molecular Weight: | 576 |
| NCBI Full Name: | Coilin |
| NCBI Synonym Full Names: | coilin |
| NCBI Official Symbol: | COIL |
| NCBI Official Synonym Symbols: | CLN80; p80-coilin |
| NCBI Protein Information: | coilin; p80; coilin p80 |
| UniProt Protein Name: | Coilin |
| UniProt Synonym Protein Names: | p80-coilin |
| Protein Family: | Coilin |
| UniProt Gene Name: | COIL |
| UniProt Entry Name: | COIL_HUMAN |
 | Western blot - Coilin Rabbit mAb (CAB3483) |
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