Anti-CNP Antibody (CAB18009)[KO Validated]

(No reviews yet) Write a Review
お見積り依頼
SKU:
CAB18009
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€0.00
Frequently bought together:

Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-CNP Antibody [KO Validated]
抗体コード:CAB18009
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IHC
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 152-421 of human CNP (NP_149124.3).
申し込み:WB IHC
推奨希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:200
反応性:Human, Mouse, Rat
ポジティブサンプル:HeLa
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 152-421 of human CNP (NP_149124.3).
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:TAWR LDCA QLKE KNQW QLSA DDLK KLKP GLEK DFLP LYFG WFLT KKSS ETLR KAGQ VFLE ELGN HKAF KKEL RQFV PGDE PREK MDLV TYFG KRPP GVLH CTTK FCDY GKAP GAEE YAQQ DVLK KSYS KAFT LTIS ALFV TPKT TGAR VELS EQQL QLWP SDVD KLSP TDNL PRGS RAHI TLGC AADV EAVQ TGLD LLEI LRQE KGGS RGEE VGEL SRGK LYSL GNGR WMLT LAKN MEVR AIFT GYYG KGKP VPTQ GSRK GGAL QSCT II
遺伝子ID:1267
Uniprot:P09543
セルラーロケーション:Lipid-anchor, Melanosome, Membrane
計算された分子量:45kDa/47kDa
観察された分子量:47kDa
Anti-CNP Antibody [KO Validated] (CAB18009)Western blot analysis of extracts from normal (control) and CNP knockout (KO) HeLa cells, using CNP antibody (CAB18009) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
同義語:CNP, CNP1, CNPase
バックグラウンド:
UniProt Protein Function:CNP: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Exists as monomers and homodimers. Belongs to the cyclic nucleotide phosphodiesterase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Phosphodiesterase; EC 3.1.4.37; Cell development/differentiation

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: nucleoplasm; microtubule; extracellular space; mitochondrial outer membrane; microvillus; membrane; perinuclear region of cytoplasm; mitochondrial inner membrane; cytoplasm; melanosome; plasma membrane; pseudopodium; nucleus

Molecular Function:cyclic nucleotide binding; RNA binding; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity

Biological Process: synaptic transmission; substantia nigra development; axonogenesis; adult locomotory behavior; response to toxin; forebrain development; oligodendrocyte differentiation; response to lipopolysaccharide; microtubule cytoskeleton organization and biogenesis; regulation of mitochondrial membrane permeability; cyclic nucleotide catabolic process; aging

UniProt Code:P09543
NCBI GenInfo Identifier:1705945
NCBI Gene ID:1267
NCBI Accession:P09543.2
UniProt Related Accession:P09543
Molecular Weight:421
NCBI Full Name:2',3'-cyclic-nucleotide 3'-phosphodiesterase
NCBI Synonym Full Names:2',3'-cyclic nucleotide 3' phosphodiesterase
NCBI Official Symbol:CNP  
NCBI Official Synonym Symbols:CNP1  
NCBI Protein Information:2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNPase; 2', 3' cyclic nucleotide 3' phosphohydrolase
UniProt Protein Name:2',3'-cyclic-nucleotide 3'-phosphodiesterase
Protein Family:2',3'-cyclic-nucleotide 3'-phosphodiesterase
UniProt Gene Name:CNP  
UniProt Entry Name:CN37_HUMAN
View AllClose

View AllClose