Anti-CNOT8 Antibody (CAB8058)
- SKU:
- CAB8058
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | CNOT8 Rabbit Polyclonal Antibody |
抗体コード: | CAB8058 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human CNOT8 (NP_004770.4). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | 293T, Mouse liver, Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human CNOT8 (NP_004770.4). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MPAA LVEN SQVI CEVW ASNL EEEM RKIR EIVL SYSY IAMD TEFP GVVV RPIG EFRS SIDY QYQL LRCN VDLL KIIQ LGLT FTNE KGEY PSGI NTWQ FNFK FNLT EDMY SQDS IDLL ANSG LQFQ KHEE EGID TLHF AELL MTSG VVLC DNVK WLSF HSGY DFGY MVKL LTDS RLPE EEHE FFHI LNLF FPSI YDVK YLMK SCKN LKGG LQEV ADQL DLQR IGRQ HQAG SDSL LTGM AFFR MKEL FFED SIDD AKYC GRLY GLGT GVAQ KQNE DVDS AQEK MSIL AIIN NMQQ |
遺伝子ID: | 9337 |
Uniprot: | Q9UFF9 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 21kDa/27kDa/33kDa |
観察された分子量: | 34kDa |
同義語: | CNOT8, CAF1, CALIF, Caf1b, POP2, hCAF1 |
バックグラウンド: |
UniProt Protein Function: | CNOT8: Ubiquitous transcription factor required for a diverse set of processes. The CCR4-NOT complex functions as general transcription regulation complex. Belongs to the CAF1 family. |
UniProt Protein Details: | Protein type:EC 3.1.13.4 Chromosomal Location of Human Ortholog: 5q31-q33 Cellular Component: intracellular; cytosol; nucleus; CCR4-NOT complex Molecular Function:protein binding; 3'-5'-exoribonuclease activity; poly(A)-specific ribonuclease activity; RNA binding; metal ion binding; transcription factor activity Biological Process: regulation of translation; negative regulation of cell proliferation; poly(A) tail shortening; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; gene expression; miRNA-mediated gene silencing; mRNA catabolic process, deadenylation-dependent decay |
UniProt Code: | Q9UFF9 |
NCBI GenInfo Identifier: | 15213949 |
NCBI Gene ID: | 9337 |
NCBI Accession: | Q9UFF9.1 |
UniProt Secondary Accession: | Q9UFF9,O95709, Q7Z521, Q9H6Y1, B0AZS3, B2RAR8, B7Z8R1 D3DQI8, |
UniProt Related Accession: | Q9UFF9 |
Molecular Weight: | 27,415 Da |
NCBI Full Name: | CCR4-NOT transcription complex subunit 8 |
NCBI Synonym Full Names: | CCR4-NOT transcription complex, subunit 8 |
NCBI Official Symbol: | CNOT8 |
NCBI Official Synonym Symbols: | CAF1; POP2; CALIF; Caf1b; hCAF1 |
NCBI Protein Information: | CCR4-NOT transcription complex subunit 8; CAF2; CALIFp; CAF1-like protein; CCR4-associated factor 8; PGK promoter directed over production |
UniProt Protein Name: | CCR4-NOT transcription complex subunit 8 |
UniProt Synonym Protein Names: | CAF1-like protein; CALIFp; CAF2; CCR4-associated factor 8; Caf1b |
Protein Family: | CCR4-NOT transcription complex |
UniProt Gene Name: | CNOT8 |
UniProt Entry Name: | CNOT8_HUMAN |
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