Anti-CLTC Antibody (CAB7886)
- SKU:
- CAB7886
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Description
| 抗体名: | Anti-CLTC Antibody |
| 抗体コード: | CAB7886 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of human CLTC |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, BT-474, Mouse brain, Mouse lung, Rat brain |
| 免疫原: | A synthetic peptide of human CLTC |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 1213 |
| Uniprot: | Q00610 |
| セルラーロケーション: | Cytoplasmic side, Cytoplasmic vesicle membrane, Melanosome, Membrane, Peripheral membrane protein, coated pit |
| 計算された分子量: | 187kDa/191kDa |
| 観察された分子量: | 180kDa |
| 同義語: | CLTC, CHC, CHC17, CLH-17, CLTCL2, Hc |
| バックグラウンド: | Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. |
| UniProt Protein Function: | CLTC: a major protein component of the cytoplasmic face of coated vesicles and coated pits. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Vesicle Chromosomal Location of Human Ortholog: 17q23.1 Cellular Component: clathrin coat; clathrin-coated vesicle; cytosol; endosome; extracellular matrix; focal adhesion; lysosome; membrane; plasma membrane; protein complex; spindle; trans-Golgi network membrane Molecular Function:clathrin light chain binding; double-stranded RNA binding; protein binding; protein kinase binding; RNA binding Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; clathrin cage assembly; microtubule-based movement; mitotic cell cycle; osteoblast differentiation; receptor internalization; receptor-mediated endocytosis; retrograde transport, endosome to Golgi; transferrin transport; Wnt receptor signaling pathway, planar cell polarity pathway |
| NCBI Summary: | Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q00610 |
| NCBI GenInfo Identifier: | 1705916 |
| NCBI Gene ID: | 1213 |
| NCBI Accession: | Q00610.5 |
| UniProt Secondary Accession: | Q00610,Q6N0A0, Q86TF2, D3DU00, |
| UniProt Related Accession: | Q00610 |
| Molecular Weight: | 192kDa |
| NCBI Full Name: | Clathrin heavy chain 1 |
| NCBI Synonym Full Names: | clathrin heavy chain |
| NCBI Official Symbol: | CLTC |
| NCBI Official Synonym Symbols: | Hc; CHC; CHC17; CLH-17; CLTCL2 |
| NCBI Protein Information: | clathrin heavy chain 1 |
| UniProt Protein Name: | Clathrin heavy chain 1 |
| UniProt Synonym Protein Names: | Clathrin heavy chain on chromosome 17; CLH-17 |
| Protein Family: | Clathrin |
| UniProt Gene Name: | CLTC |
 | Western blot analysis of extracts of various cell lines, using CLTC antibody (CAB7886) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human stomach using CLTC antibody (CAB7886) (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using CLTC antibody (CAB7886) (40x lens). |