Anti-CLPX Antibody (CAB17088)
- SKU:
- CAB17088
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-CLPX Antibody |
| 抗体コード: | CAB17088 |
| 抗体サイズ: | 20uL, 50 uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human CLPX (NP_006651.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human CLPX (NP_006651.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LPVV VPLH SLDE KTLV QILT EPRN AVIP QYQA LFSM DKCE LNVT EDAL KAIA RLAL ERKT GARG LRSI MEKL LLEP MFEV PNSD IVCV EVDK EVVE GKKE P |
| 遺伝子ID: | 10845 |
| Uniprot: | O76031 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | CLPX |
| バックグラウンド: | The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. |
| UniProt Protein Function: | CLPX: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of clpP. Belongs to the ClpX chaperone family. |
| UniProt Protein Details: | Protein type:Activator; Mitochondrial; Chaperone; Protease Chromosomal Location of Human Ortholog: 15q22.31 Cellular Component: cytoplasm; mitochondrial inner membrane; mitochondrial matrix; mitochondrion; nucleoplasm Molecular Function:ATP binding; ATP-dependent peptidase activity; ATPase activity; protease activator activity; protein binding Biological Process: proteolysis involved in cellular protein catabolic process |
| NCBI Summary: | The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015] |
| UniProt Code: | O76031 |
| NCBI GenInfo Identifier: | 14916956 |
| NCBI Gene ID: | 10845 |
| NCBI Accession: | O76031.2 |
| UniProt Secondary Accession: | O76031,Q9H4D9, A1L428, A8K8F1, B9EGI8, |
| UniProt Related Accession: | O76031 |
| Molecular Weight: | 69,224 Da |
| NCBI Full Name: | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial |
| NCBI Synonym Full Names: | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| NCBI Official Symbol: | CLPX |
| NCBI Protein Information: | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial |
| UniProt Protein Name: | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial |
| Protein Family: | ATP-dependent Clp protease ATP-binding |
| UniProt Gene Name: | CLPX |
| UniProt Entry Name: | CLPX_HUMAN |