Anti-CLEC12A Antibody (CAB6250)
- SKU:
- CAB6250
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CLEC12A Antibody |
抗体コード: | CAB6250 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 66-265 of human CLEC12A (NP_612210.4). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | K-562 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 66-265 of human CLEC12A (NP_612210.4). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | VTLK IEMK KMNK LQNI SEEL QRNI SLQL MSNM NISN KIRN LSTT LQTI ATKL CREL YSKE QEHK CKPC PRRW IWHK DSCY FLSD DVQT WQES KMAC AAQN ASLL KINN KNAL EFIK SQSR SYDY WLGL SPEE DSTR GMRV DNII NSSA WVIR NAPD LNNM YCGY INRL YVQY YHCT YKKR MICE KMAN PVQL GSTY FREA |
遺伝子ID: | 160364 |
Uniprot: | Q5QGZ9 |
セルラーロケーション: | Cell membrane, Single-pass type II membrane protein |
計算された分子量: | 8kDa/24kDa/27kDa/30kDa/32kDa |
観察された分子量: | 24kDa |
同義語: | CLEC12A, CD371, CLL-1, CLL1, DCAL-2, MICL |
バックグラウンド: | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. |
UniProt Protein Function: | CLEC12A: Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 12p13.31 |
NCBI Summary: | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011] |
UniProt Code: | Q5QGZ9 |
NCBI GenInfo Identifier: | 308153619 |
NCBI Gene ID: | 160364 |
NCBI Accession: | Q5QGZ9.3 |
UniProt Secondary Accession: | Q5QGZ9,Q6P4H1, Q6RH77, Q6RH78, Q8TDQ6, B2RA16, |
UniProt Related Accession: | Q5QGZ9 |
Molecular Weight: | |
NCBI Full Name: | C-type lectin domain family 12 member A |
NCBI Synonym Full Names: | C-type lectin domain family 12 member A |
NCBI Official Symbol: | CLEC12A |
NCBI Official Synonym Symbols: | CLL1; MICL; CD371; CLL-1; DCAL-2 |
NCBI Protein Information: | C-type lectin domain family 12 member A |
UniProt Protein Name: | C-type lectin domain family 12 member A |
UniProt Synonym Protein Names: | C-type lectin-like molecule 1; CLL-1; Dendritic cell-associated lectin 2; DCAL-2; Myeloid inhibitory C-type lectin-like receptor; MICL |
Protein Family: | C-type lectin domain family |
UniProt Gene Name: | CLEC12A |
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