Anti-CLDN17 Antibody (CAB15151)
- SKU:
- CAB15151
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-CLDN17 Antibody |
| 抗体コード: | CAB15151 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human CLDN17 (NP_036263.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse kidney, Rat kidney |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human CLDN17 (NP_036263.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CGMK QVQC TGSN ERAK AYLL GTSG VLFI LTGI FVLI PVSW TANI IIRD FYNP AIHI GQKR ELGA ALFL GWAS AAVL FIGG GLLC GFCC CNRK KQGY RYPV PGYR VPHT DKRR NTTM LSKT STSY V |
| 遺伝子ID: | 26285 |
| Uniprot: | P56750 |
| セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction |
| 計算された分子量: | 24kDa |
| 観察された分子量: | 29kDa |
| 同義語: | CLDN17 |
| バックグラウンド: | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. |
| UniProt Protein Function: | Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability. |
| NCBI Summary: | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. [provided by RefSeq, Jun 2010] |
| UniProt Code: | P56750 |
| NCBI GenInfo Identifier: | 6912316 |
| NCBI Gene ID: | 26285 |
| NCBI Accession: | NP_036263.1 |
| UniProt Secondary Accession: | P56750,Q3MJB5, Q6UY37, |
| UniProt Related Accession: | P56750 |
| Molecular Weight: | 25 kDa |
| NCBI Full Name: | claudin-17 |
| NCBI Synonym Full Names: | claudin 17 |
| NCBI Official Symbol: | CLDN17 |
| NCBI Protein Information: | claudin-17 |
| UniProt Protein Name: | Claudin-17 |
| Protein Family: | Claudin |
| UniProt Gene Name: | CLDN17 |
 | Western blot analysis of extracts of various cell lines, using CLDN17 antibody (CAB15151) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded mouse kidney using CLDN17 antibody (CAB15151) at dilution of 1:100 (40x lens). |
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