Anti-CLC Antibody (CAB15265)
- SKU:
- CAB15265
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CLC Antibody |
| 抗体コード: | CAB15265 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human CLC (NP_001819.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HepG2, HL-60 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human CLC (NP_001819.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSLL PVPY TEAA SLST GSTV TIKG RPLA CFLN EPYL QVDF HTEM KEES DIVF HFQV CFGR RVVM NSRE YGAW KQQV ESKN MPFQ DGQE FELS ISVL PDKY QVMV NGQS SYTF DHRI KPEA VKMV QVWR DISL TKFN VSYL KR |
| 遺伝子ID: | 1178 |
| Uniprot: | Q05315 |
| セルラーロケーション: | Cytoplasm, Cytoplasmic granule, cytosol |
| 計算された分子量: | 16kDa |
| 観察された分子量: | 14kDa |
| 同義語: | CLC, GAL10, Gal-10, LGALS10, LGALS10A, LPPL_HUMAN |
| バックグラウンド: | Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. |
| UniProt Protein Function: | Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg). |
| NCBI Summary: | Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q05315 |
| NCBI GenInfo Identifier: | 317373429 |
| NCBI Gene ID: | 1178 |
| NCBI Accession: | Q05315.3 |
| UniProt Secondary Accession: | Q05315,Q0VDE3, C5HZ13, C5HZ14, |
| UniProt Related Accession: | Q05315 |
| Molecular Weight: | 16,453 Da |
| NCBI Full Name: | Galectin-10 |
| NCBI Synonym Full Names: | Charcot-Leyden crystal galectin |
| NCBI Official Symbol: | CLC |
| NCBI Official Synonym Symbols: | GAL10; Gal-10; LGALS10; LGALS10A; LPPL_HUMAN |
| NCBI Protein Information: | galectin-10 |
| UniProt Protein Name: | Galectin-10 |
| UniProt Synonym Protein Names: | Charcot-Leyden crystal protein; CLC; Eosinophil lysophospholipase; Lysolecithin acylhydrolase |
| Protein Family: | Clathrin |
| UniProt Gene Name: | CLC |
| UniProt Entry Name: | LEG10_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CLC antibody (CAB15265) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90S. |
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