Anti-CKMT2 Antibody (CAB2206)
- SKU:
- CAB2206
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CKMT2 Antibody |
抗体コード: | CAB2206 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-230 of human CKMT2 (NP_001816.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse skeletal muscle, Mouse heart, Rat skeletal muscle |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-230 of human CKMT2 (NP_001816.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | EVRE QPRL FPPS ADYP DLRK HNNC MAEC LTPA IYAK LRNK VTPN GYTL DQCI QTGV DNPG HPFI KTVG MVAG DEES YEVF ADLF DPVI KLRH NGYD PRVM KHTT DLDA SKIT QGQF DEHY VLSS RVRT GRSI RGLS LPPA CTRA ERRE VENV AITA LEGL KGDL AGRY YKLS EMTE QDQQ RLID DHFL FDK |
遺伝子ID: | 1160 |
Uniprot: | P17540 |
セルラーロケーション: | Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein |
計算された分子量: | 47kDa |
観察された分子量: | 48kDa |
同義語: | CKMT2, SMTCK |
バックグラウンド: | Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. |
UniProt Protein Function: | CKMT2: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family. |
UniProt Protein Details: | Protein type:Mitochondrial; Amino Acid Metabolism - arginine and proline; Kinase, other; EC 2.7.3.2 Chromosomal Location of Human Ortholog: 5q13.3 Cellular Component: mitochondrial inner membrane; mitochondrion Molecular Function:creatine kinase activity Biological Process: creatine metabolic process; muscle contraction |
NCBI Summary: | Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P17540 |
NCBI GenInfo Identifier: | 116242603 |
NCBI Gene ID: | 1160 |
NCBI Accession: | P17540.2 |
UniProt Secondary Accession: | P17540,Q6ICS8, Q8N1E1, |
UniProt Related Accession: | P17540 |
Molecular Weight: | 47,504 Da |
NCBI Full Name: | Creatine kinase S-type, mitochondrial |
NCBI Synonym Full Names: | creatine kinase, mitochondrial 2 |
NCBI Official Symbol: | CKMT2 |
NCBI Official Synonym Symbols: | SMTCK |
NCBI Protein Information: | creatine kinase S-type, mitochondrial |
UniProt Protein Name: | Creatine kinase S-type, mitochondrial |
UniProt Synonym Protein Names: | Basic-type mitochondrial creatine kinase; Mib-CK; Sarcomeric mitochondrial creatine kinase; S-MtCK |
Protein Family: | Creatine kinase |
UniProt Gene Name: | CKMT2 |
UniProt Entry Name: | KCRS_HUMAN |
View AllClose