Anti-CKLF Antibody (CAB16528)
- SKU:
- CAB16528
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CKLF Antibody |
抗体コード: | CAB16528 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-67 of human CKLF (NP_057410.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse thymus, Mouse testis, Rat thymus, Rat testis |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-67 of human CKLF (NP_057410.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MDNV QPKI KHRP FCFS VKGH VKML RLVF ALVT AVCC LADG ALIY RKLL FNPS GPYQ KKPV HEKK EVL |
遺伝子ID: | 51192 |
Uniprot: | Q9UBR5 |
セルラーロケーション: | Membrane, Multi-pass membrane protein, Secreted |
計算された分子量: | 7kDa/10kDa/12kDa/13kDa/17kDa |
観察された分子量: | 13kDa |
同義語: | CKLF, C32, CKLF1, CKLF2, CKLF3, CKLF4, HSPC224, UCK-1 |
バックグラウンド: | The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1). |
UniProt Protein Function: | CKLF: May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10. Belongs to the chemokine-like factor family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Chemokine; Motility/polarity/chemotaxis; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 16q21 Cellular Component: cell; extracellular region; extracellular space; integral to membrane; membrane Molecular Function:chemokine activity Biological Process: cell proliferation; lymphocyte chemotaxis; macrophage chemotaxis; neutrophil chemotaxis; secretion by cell |
NCBI Summary: | The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011] |
UniProt Code: | Q9UBR5 |
NCBI GenInfo Identifier: | 34098753 |
NCBI Gene ID: | 51192 |
NCBI Accession: | Q9UBR5.1 |
UniProt Secondary Accession: | Q9UBR5,Q9UHM7, Q9UHN8, Q9UI41, C9JE38, |
UniProt Related Accession: | Q9UBR5 |
Molecular Weight: | 12,888 Da |
NCBI Full Name: | Chemokine-like factor |
NCBI Synonym Full Names: | chemokine-like factor |
NCBI Official Symbol: | CKLF |
NCBI Official Synonym Symbols: | C32; CKLF1; CKLF2; CKLF3; CKLF4; UCK-1; HSPC224 |
NCBI Protein Information: | chemokine-like factor |
UniProt Protein Name: | Chemokine-like factor |
UniProt Synonym Protein Names: | C32 |
Protein Family: | Chemokine-like factor |
UniProt Gene Name: | CKLF |
UniProt Entry Name: | CKLF_HUMAN |
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