Anti-CIZ1 Antibody (CAB17349)
- SKU:
- CAB17349
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CIZ1 Antibody |
| 抗体コード: | CAB17349 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-440 of human CIZ1 (NP_001124490). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | mouse testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-440 of human CIZ1 (NP_001124490). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PGQL QVKA QPQA RMTV PKQT QTPD LLPE ALEA QVLP RFQP RVLQ VQAQ VQSQ TQPR IPST DTQV QPKL QKQA QTQT SPEH LVLQ QKQV QPQL QQEA EPQK QVQP QVHT QAQP SVQP QEHP PAQV SVQP PEQT HEQP HTQP QVSL LAPE QTPV VVHV CGLE MPPD AVEA GGGM EKTL PEPV GTQV SMEE IQN |
| 遺伝子ID: | 25792 |
| Uniprot: | Q9ULV3 |
| セルラーロケーション: | |
| 計算された分子量: | 100kDa |
| 観察された分子量: | 100kDa |
| 同義語: | CIZ1, LSFR1, NP94, ZNF356 |
| バックグラウンド: | The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | CIZ1: May regulate the subcellular localization of CIP/WAF1. Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of the neck muscles, which produce abnormal posturing of the head upon the trunk. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 9q34.1 Cellular Component: nucleus Molecular Function:protein binding; nucleic acid binding; zinc ion binding |
| NCBI Summary: | The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| UniProt Code: | Q9ULV3 |
| NCBI GenInfo Identifier: | 42544179 |
| NCBI Gene ID: | 25792 |
| NCBI Accession: | NP_036259.2 |
| UniProt Secondary Accession: | Q9ULV3,Q5SYW3, Q5SYW5, Q8WU72, Q9H868, Q9NYM8, Q9UHK4 Q9Y3F9, Q9Y3G0, A8K9J8, B4E131, B7ZAS8, |
| UniProt Related Accession: | Q9ULV3 |
| Molecular Weight: | 88,520 Da |
| NCBI Full Name: | cip1-interacting zinc finger protein isoform 1 |
| NCBI Synonym Full Names: | CDKN1A interacting zinc finger protein 1 |
| NCBI Official Symbol: | CIZ1 |
| NCBI Official Synonym Symbols: | NP94; LSFR1; ZNF356 |
| NCBI Protein Information: | cip1-interacting zinc finger protein; nuclear protein NP94; zinc finger protein 356 |
| UniProt Protein Name: | Cip1-interacting zinc finger protein |
| UniProt Synonym Protein Names: | CDKN1A-interacting zinc finger protein 1; Nuclear protein NP94; Zinc finger protein 356 |
| Protein Family: | Cip1-interacting zinc finger protein |
| UniProt Gene Name: | CIZ1 |
| UniProt Entry Name: | CIZ1_HUMAN |
 | Western blot analysis of extracts of mouse testis, using CIZ1 antibody (CAB17349) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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