Anti-CISD1 Antibody (CAB10317)
- SKU:
- CAB10317
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CISD1 Antibody |
| 抗体コード: | CAB10317 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-108 of human CISD1 (NP_060934.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:1000 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, Mouse liver, Mouse heart, Mouse skeletal muscle, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-108 of human CISD1 (NP_060934.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LAYK RFYV KDHR NKAM INLH IQKD NPKI VHAF DMED LGDK AVYC RCWR SKKF PFCD GAHT KHNE ETGD NVGP LIIK KKET |
| 遺伝子ID: | 55847 |
| Uniprot: | Q9NZ45 |
| セルラーロケーション: | Mitochondrion outer membrane, Single-pass type III membrane protein |
| 計算された分子量: | 12kDa |
| 観察された分子量: | 12kDa |
| 同義語: | CISD1, C10orf70, MDS029, ZCD1, mitoNEET |
| バックグラウンド: | This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. |
| UniProt Protein Function: | ZCD1: Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Mitochondrial Chromosomal Location of Human Ortholog: 10q21.1 Cellular Component: mitochondrion |
| NCBI Summary: | This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q9NZ45 |
| NCBI GenInfo Identifier: | 25453105 |
| NCBI Gene ID: | 55847 |
| NCBI Accession: | Q9NZ45.1 |
| UniProt Secondary Accession: | Q9NZ45,Q1X902, |
| UniProt Related Accession: | Q9NZ45 |
| Molecular Weight: | 12kDa |
| NCBI Full Name: | CDGSH iron-sulfur domain-containing protein 1 |
| NCBI Synonym Full Names: | CDGSH iron sulfur domain 1 |
| NCBI Official Symbol: | CISD1 |
| NCBI Official Synonym Symbols: | ZCD1; MDS029; C10orf70; mitoNEET |
| NCBI Protein Information: | CDGSH iron-sulfur domain-containing protein 1 |
| UniProt Protein Name: | CDGSH iron-sulfur domain-containing protein 1 |
| UniProt Synonym Protein Names: | MitoNEET |
| Protein Family: | CDGSH iron-sulfur domain-containing protein |
| UniProt Gene Name: | CISD1 |
 | Western blot analysis of extracts of various cell lines, using CISD1 antibody (CAB10317) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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