Anti-CIR1 Antibody (CAB10133)
- SKU:
- CAB10133
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-CIR1 Antibody |
抗体コード: | CAB10133 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human CIR1 (NP_004873.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | U2OS |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human CIR1 (NP_004873.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MGKS FANF MCKK DFHP ASKS NIKK VWMA EQKI SYDK KKQE ELMQ QYLK EQES YDNR LLMG DERV KNGL NFMY EAPP GAKK ENKE KEET EGET EYKF EWQK GAPR EKYA KDDM NIRD QPFG IQVR NVRC IKCH KWGH VNTD RECP LFGL SGIN ASSV PTDG |
遺伝子ID: | 9541 |
Uniprot: | Q86X95 |
セルラーロケーション: | Cytoplasm, Nucleus speckle, centrosome, cytoskeleton, microtubule organizing center |
計算された分子量: | 23kDa/52kDa |
観察された分子量: | 52kDa |
同義語: | CIR1, CIR |
バックグラウンド: |
UniProt Protein Function: | CIR: May modulate splice site selection during alternative splicing of pre-mRNAs. Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2q31.1 Cellular Component: histone deacetylase complex; nucleus Molecular Function:protein binding; RNA polymerase II transcription factor activity, enhancer binding; transcription corepressor activity; transcription factor activity Biological Process: negative regulation of transcription, DNA-dependent |
UniProt Code: | Q86X95 |
NCBI GenInfo Identifier: | 74727790 |
NCBI Gene ID: | 9541 |
NCBI Accession: | Q86X95.1 |
UniProt Secondary Accession: | Q86X95,O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2, A6NFI6 A8K8M4, |
UniProt Related Accession: | Q86X95 |
Molecular Weight: | 23,274 Da |
NCBI Full Name: | Corepressor interacting with RBPJ 1 |
NCBI Synonym Full Names: | corepressor interacting with RBPJ, 1 |
NCBI Official Symbol: | CIR1 |
NCBI Official Synonym Symbols: | CIR |
NCBI Protein Information: | corepressor interacting with RBPJ 1 |
UniProt Protein Name: | Corepressor interacting with RBPJ 1 |
UniProt Synonym Protein Names: | CBF1-interacting corepressor; Recepin |
Protein Family: | Circulin |
UniProt Gene Name: | CIR1 |
UniProt Entry Name: | CIR1_HUMAN |
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