Anti-CHRM5 Antibody (CAB16293)
- SKU:
- CAB16293
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CHRM5 Antibody |
| 抗体コード: | CAB16293 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-430 of human CHRM5 (NP_036257.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-430 of human CHRM5 (NP_036257.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LQGS DSVT KAEK RKPA HRAL FRSC LRCP RPTL AQRE RNQA SWSS SRRS TSTT GKPS QATG PSAN WAKA EQLT TCSS YPSS EDED KPAT DPVL QVVY KSQG KESP GEEF SAEE TEET FVKA ETEK SDYD TPNY LLSP AAAH RPKS QKCV AYKF RLVV KADG NQET NNGC HKVK IMPC PFPV AKEP STKG LNPN PSHQ MTKR K |
| 遺伝子ID: | 1133 |
| Uniprot: | P08912 |
| セルラーロケーション: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse |
| 計算された分子量: | 60kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | CHRM5, HM5 |
| バックグラウンド: | The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. |
| UniProt Protein Function: | mAChR M5: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 15q26 Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction Molecular Function:phosphoinositide phospholipase C activity; G-protein coupled acetylcholine receptor activity Biological Process: dopamine transport; gastric acid secretion; cell proliferation; acetylcholine receptor signaling, muscarinic pathway; metabolic process; muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway; transmission of nerve impulse |
| NCBI Summary: | The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P08912 |
| NCBI GenInfo Identifier: | 543761 |
| NCBI Gene ID: | 1133 |
| NCBI Accession: | P08912.2 |
| UniProt Secondary Accession: | P08912,Q96RG7, |
| UniProt Related Accession: | P08912 |
| Molecular Weight: | 532 |
| NCBI Full Name: | Muscarinic acetylcholine receptor M5 |
| NCBI Synonym Full Names: | cholinergic receptor, muscarinic 5 |
| NCBI Official Symbol: | CHRM5 |
| NCBI Official Synonym Symbols: | HM5 |
| NCBI Protein Information: | muscarinic acetylcholine receptor M5; acetylcholine receptor, muscarinic 5 |
| UniProt Protein Name: | Muscarinic acetylcholine receptor M5 |
| Protein Family: | Muscarinic acetylcholine receptor |
| UniProt Gene Name: | CHRM5 |
| UniProt Entry Name: | ACM5_HUMAN |
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