Anti-CHRAC1 Antibody (CAB7372)
- SKU:
- CAB7372
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CHRAC1 Antibody |
| 抗体コード: | CAB7372 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human CHRAC1 (NP_059140.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, A-549, HepG2, 293T, BxPC-3 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human CHRAC1 (NP_059140.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MADV VVGK DKGG EQRL ISLP LSRI RVIM KSSP EVSS INQE ALVL TAKA TELF VQCL ATYS YRHG SGKE KKVL TYSD LANT AQQS ETFQ FLAD ILPK KILA SKYL KMLK EEKR EEDE ENDN DNES DHDE ADS |
| 遺伝子ID: | 54108 |
| Uniprot: | Q9NRG0 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 14kDa |
| 観察された分子量: | 15kDa |
| 同義語: | CHRAC1, CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1 |
| バックグラウンド: |
| UniProt Protein Function: | CHRAC1: Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: epsilon DNA polymerase complex; chromatin accessibility complex Molecular Function:DNA binding; sequence-specific DNA binding; protein heterodimerization activity; DNA-directed DNA polymerase activity Biological Process: chromatin remodeling |
| NCBI Summary: | CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9NRG0 |
| NCBI GenInfo Identifier: | 22653683 |
| NCBI Gene ID: | 54108 |
| NCBI Accession: | Q9NRG0.1 |
| UniProt Related Accession: | Q9NRG0 |
| Molecular Weight: | 14,711 Da |
| NCBI Full Name: | Chromatin accessibility complex protein 1 |
| NCBI Synonym Full Names: | chromatin accessibility complex 1 |
| NCBI Official Symbol: | CHRAC1 |
| NCBI Official Synonym Symbols: | YCL1; CHARC1; CHARC15; CHRAC-1; CHRAC15; CHRAC-15 |
| NCBI Protein Information: | chromatin accessibility complex protein 1; DNA polymerase epsilon subunit p15; chromatin accessibility complex 15 kDa protein; histone-fold protein CHRAC15 |
| UniProt Protein Name: | Chromatin accessibility complex protein 1 |
| UniProt Synonym Protein Names: | Chromatin accessibility complex 15 kDa protein; CHRAC-15; HuCHRAC15; DNA polymerase epsilon subunit p15 |
| Protein Family: | Chromatin accessibility complex protein |
| UniProt Gene Name: | CHRAC1 |
| UniProt Entry Name: | CHRC1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CHRAC1 antibody (CAB7372) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded mouse brain using CHRAC1 antibody (CAB7372) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using CHRAC1 antibody (CAB7372) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of U2OS cells using CHRAC1 Rabbit pAb (CAB7372) at dilution of 1:100. Blue: DAPI for nuclear staining. |
View AllClose