Anti-CHD4 Antibody (CAB11574)
- SKU:
- CAB11574
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-CHD4 Antibody |
抗体コード: | CAB11574 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1690 of human CHD4 (NP_001264.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, Jurkat, 293T, HT-1080 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1690 of human CHD4 (NP_001264.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ELAE VEEN KKMS QPGS PSPK TPTP STPG DTQP NTPA PVPP AEDG IKIE ENSL KEEE SIEG EKEV KSTA PETA IECT QAPA PASE DEKV VVEP PEGE EKVE KAEV KERT EEPM ETEP KGAA DVEK VEEK SAID LTPI VVED KEEK KEEE EKKE VMLQ NGET PKDL NDEK QKK |
遺伝子ID: | 1108 |
Uniprot: | Q14839 |
セルラーロケーション: | Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center |
計算された分子量: | 218kDa/220kDa |
観察された分子量: | 280kDa |
同義語: | CHD4, CHD-4, Mi-2b, Mi2-BETA, SIHIWES |
バックグラウンド: | The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Protein Function: | Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. |
NCBI Summary: | The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] |
UniProt Code: | Q14839 |
NCBI GenInfo Identifier: | 311033360 |
NCBI Gene ID: | 1108 |
NCBI Accession: | Q14839.2 |
UniProt Secondary Accession: | Q14839,Q8IXZ5, |
UniProt Related Accession: | Q14839 |
Molecular Weight: | 278 kDa |
NCBI Full Name: | Chromodomain-helicase-DNA-binding protein 4 |
NCBI Synonym Full Names: | chromodomain helicase DNA binding protein 4 |
NCBI Official Symbol: | CHD4 |
NCBI Official Synonym Symbols: | CHD-4; Mi-2b; SIHIWES; Mi2-BETA |
NCBI Protein Information: | chromodomain-helicase-DNA-binding protein 4 |
UniProt Protein Name: | Chromodomain-helicase-DNA-binding protein 4 |
UniProt Synonym Protein Names: | ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi2-beta |
Protein Family: | Chromodomain-helicase-DNA-binding protein |
UniProt Gene Name: | CHD4 |
View AllClose