Anti-CHCHD3 Antibody (CAB8584)
- SKU:
- CAB8584
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-CHCHD3 Antibody |
抗体コード: | CAB8584 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF IP |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human CHCHD3 (NP_060282.1). |
申し込み: | WB IHC IF IP |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 IP 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-549, HeLa, A-431, Jurkat, HepG2, mouse kidney, mouse liver, rat heart, rat kidney, Mouse kidney, Mouse liver, Mouse heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human CHCHD3 (NP_060282.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MGGT TSTR RVTF EADE NENI TVVK GIRL SENV IDRM KESS PSGS KSQR YSGA YGAS VSDE ELKR RVAE ELAL EQAK KESE DQKR LKQA KELD RERA AANE QLTR AILR ERIC SEEE RAKA KHLA RQLE EKDR VLKK QDAF YKEQ LARL EERS SEFY RVTT EQYQ KAAE EVEA KFKR YESH PVCA DLQA KILQ CYRE NTHQ TLKC SALA TQYM HCVN HAKQ SMLE KGG |
遺伝子ID: | 54927 |
Uniprot: | Q9NX63 |
セルラーロケーション: | Cytoplasm, Intermembrane side, Lipid-anchor, Mitochondrion, Mitochondrion inner membrane, Nucleus |
計算された分子量: | 26kDa |
観察された分子量: | 30kDa |
同義語: | CHCHD3, MINOS3, Mic19, PPP1R22 |
バックグラウンド: | The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | CHCHD3: May be a scaffolding protein that stabilizes protein complexes involved in maintaining mitochondrial crista architecture and protein import. |
UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 7q33 Cellular Component: cytoplasm; mitochondrial inner membrane; mitochondrion; nucleus Molecular Function:phosphatase binding; protein binding; protein complex scaffold Biological Process: cristae formation; inner mitochondrial membrane organization and biogenesis; mitochondrial fusion; negative regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
UniProt Code: | Q9NX63 |
NCBI GenInfo Identifier: | 62510520 |
NCBI Gene ID: | 54927 |
NCBI Accession: | Q9NX63.1 |
UniProt Related Accession: | Q9NX63 |
Molecular Weight: | 26,152 Da |
NCBI Full Name: | MICOS complex subunit MIC19 |
NCBI Synonym Full Names: | coiled-coil-helix-coiled-coil-helix domain containing 3 |
NCBI Official Symbol: | CHCHD3 |
NCBI Official Synonym Symbols: | Mic19; MINOS3; PPP1R22 |
NCBI Protein Information: | MICOS complex subunit MIC19 |
UniProt Protein Name: | MICOS complex subunit MIC19 |
UniProt Synonym Protein Names: | Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 |
UniProt Gene Name: | CHCHD3 |
UniProt Entry Name: | MIC19_HUMAN |