Anti-CFHR3 Antibody (CAB7775)
- SKU:
- CAB7775
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CFHR3 Antibody |
| 抗体コード: | CAB7775 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, HepG2, NIH/3T3, 293T, Mouse liver, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-200 of human CFHR3 (NP_066303.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AVPC LRKC YFPY LENG YNQN YGRK FVQG NSTE VACH PGYG LPKA QTTV TCTE KGWS PTPR CIRV RTCS KSDI EIEN GFIS ESSS IYIL NKEI QYKC KPGY ATAD GNSS GSIT CLQN GWSA Q |
| 遺伝子ID: | 10878 |
| Uniprot: | Q02985 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 30kDa/37kDa |
| 観察された分子量: | 45kDa |
| 同義語: | CFHR3, CFHL3, DOWN16, FHR-3, FHR3, HLF4 |
| バックグラウンド: | The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | Might be involved in complement regulation. |
| NCBI Summary: | The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q02985 |
| NCBI GenInfo Identifier: | 262231791 |
| NCBI Gene ID: | 10878 |
| NCBI Accession: | NP_001160096.1 |
| UniProt Related Accession: | Q02985 |
| Molecular Weight: | |
| NCBI Full Name: | complement factor H-related protein 3 isoform 2 |
| NCBI Synonym Full Names: | complement factor H related 3 |
| NCBI Official Symbol: | CFHR3 |
| NCBI Official Synonym Symbols: | FHR3; HLF4; CFHL3; FHR-3; DOWN16 |
| NCBI Protein Information: | complement factor H-related protein 3 |
| UniProt Protein Name: | Complement factor H-related protein 3 |
| UniProt Synonym Protein Names: | DOWN16; H factor-like protein 3 |
| UniProt Gene Name: | CFHR3 |
 | Western blot analysis of extracts of various cell lines, using CFHR3 antibody (CAB7775) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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