Anti-CER1 Antibody (CAB7354)
- SKU:
- CAB7354
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CER1 Antibody |
| 抗体コード: | CAB7354 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-267 of human CER1 (NP_005445.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-267 of human CER1 (NP_005445.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TRHQ DGRQ NQSS LSPV LLPR NQRE LPTG NHEE AEEK PDLF VAVP HLVA TSPA GEGQ RQRE KMLS RFGR FWKK PERE MHPS RDSD SEPF PPGT QSLI QPID GMKM EKSP LREE AKKF WHHF MFRK TPAS QGVI LPIK SHEV HWET CRTV PFSQ TITH EGCE KVVV QNNL CFGK CGSV HFPG AAQH SHTS CSHC LPAK FTTM HLPL NCTE LSSV IKVV MLVE ECQC KVKT EHED GHIL HAGS QDSF IPGV SA |
| 遺伝子ID: | 9350 |
| Uniprot: | O95813 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 30kDa |
| 観察された分子量: | 30kDa |
| 同義語: | CER1, DAND4, cerberus |
| バックグラウンド: | This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. |
| UniProt Protein Function: | CER1: Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak. Belongs to the DAN family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted Chromosomal Location of Human Ortholog: 9p23-p22 Cellular Component: extracellular space; extracellular region Molecular Function:morphogen activity; protein homodimerization activity; cytokine activity Biological Process: BMP signaling pathway; anterior/posterior pattern formation; negative regulation of cell proliferation; nervous system development; negative regulation of activin receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud development; gastrulation; determination of dorsal identity; bone mineralization; cell migration involved in gastrulation; negative regulation of BMP signaling pathway; anterior/posterior axis specification |
| NCBI Summary: | This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95813 |
| NCBI GenInfo Identifier: | 62510411 |
| NCBI Gene ID: | 9350 |
| NCBI Accession: | O95813.1 |
| UniProt Related Accession: | O95813 |
| Molecular Weight: | |
| NCBI Full Name: | Cerberus |
| NCBI Synonym Full Names: | cerberus 1, DAN family BMP antagonist |
| NCBI Official Symbol: | CER1 |
| NCBI Official Synonym Symbols: | DAND4 |
| NCBI Protein Information: | cerberus |
| UniProt Protein Name: | Cerberus |
| UniProt Synonym Protein Names: | Cerberus-related protein; DAN domain family member 4 |
| UniProt Gene Name: | CER1 |
| UniProt Entry Name: | CER1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CER1 Antibody (CAB7354) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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