Anti-CEP350 Antibody (CAB18301)
- SKU:
- CAB18301
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-CEP350 Antibody |
| 抗体コード: | CAB18301 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human CEP350. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant protein of human CEP350. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 9857 |
| Uniprot: | Q5VT06 |
| セルラーロケーション: | |
| 計算された分子量: | 350kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | CEP350, CAP350, GM133 |
| バックグラウンド: | The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. |
| UniProt Protein Function: | CEP350: Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least, SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 1q25.2 Cellular Component: centrosome; cytoplasm; membrane; nucleoplasm; spindle Molecular Function:microtubule binding; protein binding |
| NCBI Summary: | The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q5VT06 |
| NCBI GenInfo Identifier: | 171184451 |
| NCBI Gene ID: | 9857 |
| NCBI Accession: | NP_055625.4 |
| UniProt Secondary Accession: | Q5VT06,O75068, Q8TDK3, Q8WY20, |
| UniProt Related Accession: | Q5VT06 |
| Molecular Weight: | 200kd |
| NCBI Full Name: | centrosome-associated protein 350 |
| NCBI Synonym Full Names: | centrosomal protein 350 |
| NCBI Official Symbol: | CEP350 |
| NCBI Official Synonym Symbols: | GM133; CAP350 |
| NCBI Protein Information: | centrosome-associated protein 350 |
| UniProt Protein Name: | Centrosome-associated protein 350 |
| UniProt Synonym Protein Names: | Centrosome-associated protein of 350 kDa |
| Protein Family: | Centrosome-associated protein |
| UniProt Gene Name: | CEP350 |
| UniProt Entry Name: | CE350_HUMAN |