Anti-CEP120 Antibody (CAB8004)
- SKU:
- CAB8004
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | CEP120 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8004 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CEP120 (NP_694955.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, HeLa, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CEP120 (NP_694955.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MVSK SDQL LIVV SILE GRHF PKRP KHML VVEA KFDG EQLA TDPV DHTD QPEF ATEL AWEI DRKA LHQH RLQR TPIK LQCF ALDP VTSA KETI GYIV LDLR TAQE TKQA PKWY QLLS NKYT KFKS EIQI SIAL ETDT KPPV DSFK AKGA PPRD GKVP AILA GLDP RDIV AVLN EEGG YHQI GPAE YCTD SFIM SVTI AFAT QLEQ LIPC TMKL PERQ PEFF FYYS LLGN DVTN EPFN DLIN PNFE PERA SVRI RSSV EILR VYLA LQSK LQ |
| 遺伝子ID: | 153241 |
| Uniprot: | Q8N960 |
| セルラーロケーション: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center |
| 計算された分子量: | 42kDa/109kDa/112kDa |
| 観察された分子量: | 120kDa |
| 同義語: | CEP120, CCDC100, SRTD13 |
| バックグラウンド: | This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis. |
| NCBI Summary: | This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q8N960 |
| NCBI GenInfo Identifier: | 205696377 |
| NCBI Gene ID: | 153241 |
| NCBI Accession: | Q8N960.2 |
| UniProt Secondary Accession: | Q8N960,Q6AI52, Q6AW89, Q8IWB5, Q8N9Y0, Q8NDE8, |
| UniProt Related Accession: | Q8N960 |
| Molecular Weight: | 42,705 Da |
| NCBI Full Name: | Centrosomal protein of 120 kDa |
| NCBI Synonym Full Names: | centrosomal protein 120 |
| NCBI Official Symbol: | CEP120 |
| NCBI Official Synonym Symbols: | JBTS31; SRTD13; CCDC100 |
| NCBI Protein Information: | centrosomal protein of 120 kDa |
| UniProt Protein Name: | Centrosomal protein of 120 kDa |
| UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 100 |
| Protein Family: | Centrosomal protein |
| UniProt Gene Name: | CEP120 |
 | Western blot analysis of extracts of various cell lines, using CEP120 antibody (CAB8004) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
View AllClose