Anti-CELSR2 Antibody (CAB18359)

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SKU:
CAB18359
Product type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-CELSR2 Antibody
抗体コード:CAB18359
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Mouse
宿主種:Rabbit
免疫原:Recombinant protein of human CELSR2.
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Mouse
ポジティブサンプル:
免疫原:Recombinant protein of human CELSR2.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:1952
Uniprot:Q9HCU4
セルラーロケーション:
計算された分子量:
観察された分子量:Refer to figures
同義語:ADGRC2, CDHF10, EGFL2, Flamingo1, MEGF3, CELSR2
バックグラウンド:
UniProt Protein Function:CELSR2: Receptor that may have an important role in cell/cell signaling during nervous system formation. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
UniProt Protein Details:

Protein type:Receptor, GPCR; Membrane protein, multi-pass; Cell development/differentiation; Membrane protein, integral; GPCR, family 2

Chromosomal Location of Human Ortholog: 1p21

Cellular Component: cytoplasm; integral to membrane; plasma membrane

Molecular Function:G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cerebrospinal fluid secretion; regulation of protein localization; Wnt receptor signaling pathway; regulation of cell-cell adhesion; regulation of transcription, DNA-dependent; neural plate anterioposterior pattern formation; ventricular system development; dendrite morphogenesis; neuron migration; cilium biogenesis; homophilic cell adhesion

NCBI Summary:The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008]
UniProt Code:Q9HCU4
NCBI GenInfo Identifier:22095550
NCBI Gene ID:1952
NCBI Accession:Q9HCU4.1
UniProt Secondary Accession:Q9HCU4,Q5T2Y7, Q92566,
UniProt Related Accession:Q9HCU4
Molecular Weight:317,453 Da
NCBI Full Name:Cadherin EGF LAG seven-pass G-type receptor 2
NCBI Synonym Full Names:cadherin, EGF LAG seven-pass G-type receptor 2
NCBI Official Symbol:CELSR2  
NCBI Official Synonym Symbols:EGFL2; MEGF3; CDHF10; Flamingo1  
NCBI Protein Information:cadherin EGF LAG seven-pass G-type receptor 2; EGF-like protein 2; flamingo homolog 3; cadherin family member 10; EGF-like-domain, multiple 2; epidermal growth factor-like 2; multiple EGF-like domains protein 3; epidermal growth factor-like protein 2; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
UniProt Protein Name:Cadherin EGF LAG seven-pass G-type receptor 2
UniProt Synonym Protein Names:Cadherin family member 10; Epidermal growth factor-like protein 2; EGF-like protein 2; Flamingo homolog 3; Multiple epidermal growth factor-like domains protein 3; Multiple EGF-like domains protein 3
Protein Family:Cadherin EGF LAG seven-pass G-type receptor
UniProt Gene Name:CELSR2  
UniProt Entry Name:CELR2_HUMAN
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