Anti-CECR2 Antibody (CAB10143)
- SKU:
- CAB10143
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CECR2 Antibody |
抗体コード: | CAB10143 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-370 of human CECR2 (NP_113601.2). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:1000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse liver, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-370 of human CECR2 (NP_113601.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | VQGK SNGE LSLS RESE GQKN VSSI PGKT GKRR GRPP KRKK LQEE ILLS EKQE ENSL ASEP QTRH GSQG PGQG TWWL LCQT EEEW RQVT ESFR ERTS LRER QLYK LLSE DFLP EICN MIAQ KGKR PQRT KAEL HPRW MSDH LSIK PVKQ EETP VLTR IEKQ KRKE EEEE RQIL LAVQ KKEQ EQML KEER KREL EEKV KAVE G |
遺伝子ID: | 27443 |
Uniprot: | Q9BXF3 |
セルラーロケーション: | |
計算された分子量: | 58kDa/162kDa/164kDa |
観察された分子量: | 164kDa |
同義語: | CECR2 |
バックグラウンド: | This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Chromatin reader component of histone-modifying complexes, such as the CERF (CECR2-containing-remodeling factor) complex and ISWI-type complex (PubMed:15640247, PubMed:26365797, PubMed:22464331). It thereby plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development. In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes. In histone-modifying complexes, CECR2 recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797, PubMed:22464331). May also be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis (PubMed:11827465). |
NCBI Summary: | This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
UniProt Code: | Q9BXF3 |
NCBI GenInfo Identifier: | 586798144 |
NCBI Gene ID: | 27443 |
NCBI Accession: | NP_001276976.1 |
UniProt Secondary Accession: | Q9BXF3,Q658Z4, Q96P58, Q9C0C3, A8MS90, A8MX16, |
UniProt Related Accession: | Q9BXF3 |
Molecular Weight: | 58,108 Da |
NCBI Full Name: | cat eye syndrome critical region protein 2 isoform 1 |
NCBI Synonym Full Names: | CECR2, histone acetyl-lysine reader |
NCBI Official Symbol: | CECR2 |
NCBI Protein Information: | cat eye syndrome critical region protein 2 |
UniProt Protein Name: | Cat eye syndrome critical region protein 2 |
Protein Family: | Cat eye syndrome critical region protein |
UniProt Gene Name: | CECR2 |
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