Anti-CEBPE Antibody (CAB8047)
- SKU:
- CAB8047
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | CEBPE Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8047 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CEBPE (NP_001796.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | NCI-H460, Mouse spleen |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human CEBPE (NP_001796.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSHG TYYE CEPR GGQQ PLEF SGGR AGPG ELGD MCEH EASI DLSA YIES GEEQ LLSD LFAV KPAP EARG LKGP GTPA FPHY LPPD PRPF AYPP HTFG PDRK ALGP GIYS SPGS YDPR AVAV KEEP RGPE GSRA ASRG SYNP LQYQ VAHC GQTA MHLP PTLA APGQ PLRV LKAP LATA APPC SPLL KAPS PA |
| 遺伝子ID: | 1053 |
| Uniprot: | Q15744 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 30kDa |
| 観察された分子量: | 35kDa |
| 同義語: | CEBPE, C/EBP-epsilon, CRP1 |
| バックグラウンド: | The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. |
| UniProt Protein Function: | C/EBP-epsilon: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Belongs to the bZIP family. C/EBP subfamily. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: nucleoplasm Biological Process: defense response; positive regulation of transcription from RNA polymerase II promoter Disease: Specific Granule Deficiency |
| NCBI Summary: | The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15744 |
| NCBI GenInfo Identifier: | 62512175 |
| NCBI Gene ID: | 1053 |
| NCBI Accession: | Q15744.2 |
| UniProt Secondary Accession: | Q15744,Q15745, Q8IYI2, Q99803, |
| UniProt Related Accession: | Q15744 |
| Molecular Weight: | 30,603 Da |
| NCBI Full Name: | CCAAT/enhancer-binding protein epsilon |
| NCBI Synonym Full Names: | CCAAT/enhancer binding protein epsilon |
| NCBI Official Symbol: | CEBPE |
| NCBI Official Synonym Symbols: | CRP1; C/EBP-epsilon |
| NCBI Protein Information: | CCAAT/enhancer-binding protein epsilon |
| UniProt Protein Name: | CCAAT/enhancer-binding protein epsilon |
| Protein Family: | CCAAT/enhancer-binding protein |
| UniProt Gene Name: | CEBPE |
| UniProt Entry Name: | CEBPE_HUMAN |
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