Anti-CDKN2AIP Antibody (CAB3233)
- SKU:
- CAB3233
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CDKN2AIP Antibody |
| 抗体コード: | CAB3233 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CDKN2AIP (NP_060102.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:1000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SKOV3, Mouse thymus, Rat thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CDKN2AIP (NP_060102.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAQE VSEY LSQN PRVA AWVE ALRC DGET DKHW RHRR DFLL RNAG DLAP AGGA ASAS TDEA ADAE SGTR NRQL QQLI SFSM AWAN HVFL GCRY PQKV MDKI LSMA EGIK VTDA PTYT TRDE LVAK VKKR GISS SNEG VEEP SKKR VIEG KNSS AVEQ DHAK TSAK TERA SAQQ ENSS TCIG SAIK SESG NSAR SSGI SSQN SSTS DGDR SVSS QSSS SVSS |
| 遺伝子ID: | 55602 |
| Uniprot: | Q9NXV6 |
| セルラーロケーション: | Nucleus, nucleoplasm |
| 計算された分子量: | 61kDa |
| 観察された分子量: | 65kDa |
| 同義語: | CDKN2AIP, CARF |
| バックグラウンド: | The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | CDKN2AIP: co-localizes and interacts with p14ARF in the nucleolus. Co-regulated with ARF and cooperates with it in activating p53. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 4q35.1 Cellular Component: nucleoplasm; granular component; cytoplasm; nucleolus; nucleus Molecular Function:protein binding; RNA binding; p53 binding Biological Process: positive regulation of signal transduction; regulation of protein stability; negative regulation of cell growth; response to DNA damage stimulus; positive regulation of cell growth |
| NCBI Summary: | The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
| UniProt Code: | Q9NXV6 |
| NCBI GenInfo Identifier: | 327478591 |
| NCBI Gene ID: | 55602 |
| NCBI Accession: | Q9NXV6.3 |
| UniProt Related Accession: | Q9NXV6 |
| Molecular Weight: | |
| NCBI Full Name: | CDKN2A-interacting protein |
| NCBI Synonym Full Names: | CDKN2A interacting protein |
| NCBI Official Symbol: | CDKN2AIP |
| NCBI Official Synonym Symbols: | CARF |
| NCBI Protein Information: | CDKN2A-interacting protein |
| UniProt Protein Name: | CDKN2A-interacting protein |
| UniProt Synonym Protein Names: | Collaborator of ARF |
| Protein Family: | Calcium-responsive transcription factor |
| UniProt Gene Name: | CDKN2AIP |
| UniProt Entry Name: | CARF_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CDKN2AIP antibody (CAB3233) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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