Anti-CDH18 Antibody (CAB14645)
- SKU:
- CAB14645
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CDH18 Antibody |
| 抗体コード: | CAB14645 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-500 of human CDH18 (NP_004925.1). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-500 of human CDH18 (NP_004925.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | NADM TYSI INGD GMGI FSIS TDKE TREG ILSL KKPL NYEK KKSY TLNI EGAN THLD FRFS HLGP FKDA TMLK IIVG DVDE PPLF SMPS YLME VYEN AKIG TVVG TVLA QDPD STNS LVRY FINY NVED DRFF NIDA NTGT IRTT KVLD REET PWYN ITVT ASEI DNPD LLSH VTVG IRVL DVND NPPE LARE YDII VCEN S |
| 遺伝子ID: | 1016 |
| Uniprot: | Q13634 |
| セルラーロケーション: | Cell membrane, Single-pass type I membrane protein |
| 計算された分子量: | 63kDa/88kDa |
| 観察された分子量: |
| 同義語: | CDH18, CDH14, CDH14L, CDH24 |
| バックグラウンド: | This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | CDH18: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 5p14.3 Cellular Component: integral to membrane; plasma membrane Molecular Function:calcium ion binding Biological Process: intercellular junction assembly and maintenance; homophilic cell adhesion |
| NCBI Summary: | This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] |
| UniProt Code: | Q13634 |
| NCBI GenInfo Identifier: | 4826671 |
| NCBI Gene ID: | 1016 |
| NCBI Accession: | NP_004925.1 |
| UniProt Secondary Accession: | Q13634,Q8N5Z2, A8K0I2, B4DHG6, |
| UniProt Related Accession: | Q13634 |
| Molecular Weight: | 63,677 Da |
| NCBI Full Name: | cadherin-18 isoform 1 preproprotein |
| NCBI Synonym Full Names: | cadherin 18, type 2 |
| NCBI Official Symbol: | CDH18 |
| NCBI Official Synonym Symbols: | CDH14; CDH24; CDH14L |
| NCBI Protein Information: | cadherin-18; cadherin-14; ey-cadherin; cadherin-like 24 |
| UniProt Protein Name: | Cadherin-18 |
| UniProt Synonym Protein Names: | Cadherin-14 |
| Protein Family: | Cadherin |
| UniProt Gene Name: | CDH18 |
| UniProt Entry Name: | CAD18_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat brain using CDH18 antibody (CAB14645) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse liver using CDH18 antibody (CAB14645) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse brain using CDH18 antibody (CAB14645) at dilution of 1:100 (40x lens). |
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