Anti-CDH11 Antibody (CAB14717)
- SKU:
- CAB14717
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CDH11 Antibody |
| 抗体コード: | CAB14717 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 637-796 of human CDH11 (NP_001788.2). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| 反応性: | Human, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 637-796 of human CDH11 (NP_001788.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FVTL RRQK KEPL IVFE EEDV RENI ITYD DEGG GEED TEAF DIAT LQNP DGIN GFIP RKDI KPEY QYMP RPGL RPAP NSVD VDDF INTR IQEA DNDP TAPP YDSI QIYG YEGR GSVA GSLS SLES ATTD SDLD YDYL QNWG PRFK KLAD LYGS KDTF DDDS |
| 遺伝子ID: | 1009 |
| Uniprot: | P55287 |
| セルラーロケーション: | Cell membrane, Single-pass type I membrane protein |
| 計算された分子量: | 76kDa/87kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | CDH11, CAD11, CDHOB, OB, OSF-4 |
| バックグラウンド: | This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. |
| UniProt Protein Function: | CDH11: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Interacts with PCDH8. Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 16q21 Cellular Component: cytoplasm; integral to membrane; plasma membrane Molecular Function:calcium ion binding Biological Process: intercellular junction assembly and maintenance; ossification; corticospinal tract morphogenesis; homophilic cell adhesion; cell adhesion; skeletal development |
| UniProt Code: | P55287 |
| NCBI GenInfo Identifier: | 16306532 |
| NCBI Gene ID: | 1009 |
| NCBI Accession: | NP_001788 |
| UniProt Secondary Accession: | P55287,Q15065, Q15066, Q9UQ93, Q9UQ94, A8K5D6, A8MZC8 B7WP28, |
| UniProt Related Accession: | P55287 |
| Molecular Weight: | 76,457 Da |
| NCBI Full Name: | cadherin-11 preproprotein |
| NCBI Synonym Full Names: | cadherin 11, type 2, OB-cadherin (osteoblast) |
| NCBI Official Symbol: | CDH11 |
| NCBI Official Synonym Symbols: | OB; CAD11; CDHOB; OSF-4 |
| NCBI Protein Information: | cadherin-11 |
| UniProt Protein Name: | Cadherin-11 |
| UniProt Synonym Protein Names: | OSF-4; Osteoblast cadherin |
| Protein Family: | Cadherin |
| UniProt Gene Name: | CDH11 |
| UniProt Entry Name: | CAD11_HUMAN |
 | Immunohistochemistry of paraffin-embedded Human gastric cancer using CDH11 antibody (CAB14717) at dilution of 1:100 (40x lens). |
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