| UniProt Protein Function: | Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. |
| NCBI Summary: | The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] |
| UniProt Code: | P33681 |
| NCBI GenInfo Identifier: | 461606 |
| NCBI Gene ID: | 941 |
| NCBI Accession: | P33681.1 |
| UniProt Secondary Accession: | P33681,Q5DTA9, Q5DTB0, |
| UniProt Related Accession: | P33681 |
| Molecular Weight: | 18,761 Da |
| NCBI Full Name: | T-lymphocyte activation antigen CD80 |
| NCBI Synonym Full Names: | CD80 molecule |
| NCBI Official Symbol: | CD80 |
| NCBI Official Synonym Symbols: | B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1 |
| NCBI Protein Information: | T-lymphocyte activation antigen CD80 |
| UniProt Protein Name: | T-lymphocyte activation antigen CD80 |
| UniProt Synonym Protein Names: | Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80 |
| Protein Family: | T-lymphocyte activation antigen |
| UniProt Gene Name: | CD80 |
