Anti-CD5 Antibody (CAB6882)
- SKU:
- CAB6882
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CD5 Antibody |
| 抗体コード: | CAB6882 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CD5 (NP_055022.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | SW620, BT-474, Jurkat, HepG2, Mouse spleen, Mouse thymus, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CD5 (NP_055022.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RLSW YDPD FQAR LTRS NSKC QGQL EVYL KDGW HMVC SQSW GRSS KQWE DPSQ ASKV CQRL NCGV PLSL GPFL VTYT PQSS IICY GQLG SFSN CSHS RNDM CHSL GLTC LEPQ KTTP PTTR PPPT TTPE PTAP PRLQ LVAQ SGGQ HCAG VVEF YSGS LGGT ISYE AQDK TQDL ENFL CNNL QCGS FLKH LPET EAGR AQDP GEPR EHQP LPIQ WKIQ |
| 遺伝子ID: | 921 |
| Uniprot: | P06127 |
| セルラーロケーション: | Cell membrane, Single-pass type I membrane protein |
| 計算された分子量: | 54kDa |
| 観察された分子量: | 60kDa |
| 同義語: | CD5, LEU1, T1 |
| バックグラウンド: | This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | CD5: a surface glycoprotein expressed on T cells and B-1 B cells. Rapidly recruited to the immunological synapse, lowering the response of the T cell antigen receptor. CD5 interacts with CD72/LYB-2. Promotes B-cell survival through stimulation of autocrine IL-10 production. Contains 3 SRCR domains. |
| UniProt Protein Details: | Protein type:Cell surface; Membrane protein, integral Chromosomal Location of Human Ortholog: 11q13 Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane Molecular Function:protein binding; transmembrane receptor activity; receptor activity; scavenger receptor activity Biological Process: cell proliferation; receptor-mediated endocytosis; T cell costimulation; cell recognition |
| UniProt Code: | P06127 |
| NCBI GenInfo Identifier: | 313104090 |
| NCBI Gene ID: | 921 |
| NCBI Accession: | P06127.2 |
| UniProt Secondary Accession: | P06127,A0N0P4, A8K9I3, |
| UniProt Related Accession: | P06127 |
| Molecular Weight: | 459 |
| NCBI Full Name: | T-cell surface glycoprotein CD5 |
| NCBI Synonym Full Names: | CD5 molecule |
| NCBI Official Symbol: | CD5 |
| NCBI Official Synonym Symbols: | T1; LEU1 |
| NCBI Protein Information: | T-cell surface glycoprotein CD5; CD5 antigen (p56-62); lymphocyte antigen T1/Leu-1 |
| UniProt Protein Name: | T-cell surface glycoprotein CD5 |
| UniProt Synonym Protein Names: | Lymphocyte antigen T1/Leu-1; CD_antigen: CD5 |
| Protein Family: | CD5 antigen |
| UniProt Gene Name: | CD5 |
| UniProt Entry Name: | CD5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CD5 antibody (CAB6882) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
View AllClose