Anti-CD31/PECAM1 Antibody (CAB0378)
- SKU:
- CAB0378
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CD31/PECAM1 Antibody |
抗体コード: | CAB0378 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of mouse CD31/PECAM1 (NP_001292086.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse liver |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of mouse CD31/PECAM1 (NP_001292086.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 18613 |
Uniprot: | Q08481 |
セルラーロケーション: | Cell junction, Cell junction, Cell membrane, Lipid-anchor, Single-pass type I membrane protein |
計算された分子量: | 79kDa/80kDa/81kDa/82kDa |
観察された分子量: | 130kDa |
同義語: | PECAM1, CD31, CD31/EndoCAM, GPIIA, PECA1, PECAM-1, endoCAM |
バックグラウンド: | The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. |
UniProt Protein Function: | PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Cellular Component: extracellular space; cell surface; smooth muscle contractile fiber; membrane; integral to membrane; plasma membrane; intracellular; cell junction; lipid raft; external side of plasma membrane Molecular Function:protein binding Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; wound healing; positive regulation of tyrosine phosphorylation of Stat5 protein; negative regulation of actin filament polymerization; positive regulation of leukocyte migration; diapedesis; cell adhesion; regulation of cell migration; phagocytosis; Rho protein signal transduction |
UniProt Code: | Q08481 |
NCBI GenInfo Identifier: | 585658 |
NCBI Gene ID: | 18613 |
NCBI Accession: | Q08481.1 |
UniProt Related Accession: | Q08481 |
Molecular Weight: | |
NCBI Full Name: | Platelet endothelial cell adhesion molecule |
NCBI Synonym Full Names: | platelet/endothelial cell adhesion molecule 1 |
NCBI Official Symbol: | Pecam1 |
NCBI Official Synonym Symbols: | Cd31; Pecam; C85791; PECAM-1 |
NCBI Protein Information: | platelet endothelial cell adhesion molecule |
UniProt Protein Name: | Platelet endothelial cell adhesion molecule |
UniProt Synonym Protein Names: | CD_antigen: CD31 |
UniProt Gene Name: | Pecam1 |
UniProt Entry Name: | PECA1_MOUSE |
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