Anti-CD244 Antibody (CAB1993)
- SKU:
- CAB1993
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-CD244 Antibody |
| 抗体コード: | CAB1993 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-224 of human CD244 (NP_057466.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Jurkat, 293T, Mouse spleen |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-224 of human CD244 (NP_057466.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CQGS ADHV VSIS GVPL QLQP NSIQ TKVD SIAW KKLL PSQN GFHH ILKW ENGS LPSN TSND RFSF IVKN LSLL IKAA QQQD SGLY CLEV TSIS GKVQ TATF QVFV FDKV EKPR LQGQ GKIL DRGR CQVA LSCL VSRD GNVS YAWY RGSK LIQT AGNL TYLD EEVD INGT HTYT CNVS NPVS WESH TLNL TQDC QNAH QEFR FWP |
| 遺伝子ID: | 51744 |
| Uniprot: | Q9BZW8 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 30kDa/36kDa/41kDa |
| 観察された分子量: | 36kDa |
| 同義語: | CD244, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4 |
| バックグラウンド: | This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | CD244: Modulate other receptor-ligand interactions to enhance leukocyte activation. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1q23.3 Cellular Component: plasma membrane; integral to membrane; external side of plasma membrane Molecular Function:protein binding; receptor activity Biological Process: signal transduction; blood coagulation; leukocyte migration Disease: Rheumatoid Arthritis |
| NCBI Summary: | This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] |
| UniProt Code: | Q9BZW8 |
| NCBI GenInfo Identifier: | 47605541 |
| NCBI Gene ID: | 51744 |
| NCBI Accession: | Q9BZW8.2 |
| UniProt Related Accession: | Q9BZW8 |
| Molecular Weight: | |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | CD244 molecule |
| NCBI Official Symbol: | CD244 |
| NCBI Official Synonym Symbols: | 2B4; NAIL; Nmrk; NKR2B4; SLAMF4 |
| NCBI Protein Information: | natural killer cell receptor 2B4 |
| UniProt Protein Name: | Natural killer cell receptor 2B4 |
| UniProt Synonym Protein Names: | NK cell activation-inducing ligand; NAIL; NK cell type I receptor protein 2B4; NKR2B4; h2B4; SLAM family member 4; SLAMF4; Signaling lymphocytic activation molecule 4; CD_antigen: CD244 |
| UniProt Gene Name: | CD244 |
| UniProt Entry Name: | CD244_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CD244 antibody (CAB1993) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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