Anti-CD226 Antibody (CAB10282)
- SKU:
- CAB10282
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CD226 Antibody |
| 抗体コード: | CAB10282 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-254 of human CD226 (NP_006557.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-254 of human CD226 (NP_006557.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | EEVL WHTS VPFA ENMS LECV YPSM GILT QVEW FKIG TQQD SIAI FSPT HGMV IRKP YAER VYFL NSTM ASNN MTLF FRNA SEDD VGYY SCSL YTYP QGTW QKVI QVVQ SDSF EAAV PSNS HIVS EPGK NVTL TCQP QMTW PVQA VRWE KIQP RQID LLTY CNLV HGRN FTSK FPRQ IVSN CSHG RWSV IVIP DVTV SDSG LYRC YLQA SAGE NETF VMRL TVAE GKTD NQYT LFVA |
| 遺伝子ID: | 10666 |
| Uniprot: | Q15762 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 38kDa |
| 観察された分子量: | 65kDa |
| 同義語: | CD226, DNAM-1, DNAM1, PTA1, TLiSA1 |
| バックグラウンド: | This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | DNAM-1: Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Immunoglobulin superfamily; Cell adhesion Chromosomal Location of Human Ortholog: 18q22.3 Cellular Component: cell surface; integral to plasma membrane; plasma membrane; external side of plasma membrane; lipid raft Molecular Function:integrin binding; protein binding; cell adhesion molecule binding; protein kinase binding Biological Process: regulation of immune response; positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; positive regulation of immunoglobulin mediated immune response; cytokine production; cell recognition; positive regulation of natural killer cell mediated cytotoxicity; cell adhesion; signal transduction; positive regulation of mast cell activation |
| NCBI Summary: | This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15762 |
| NCBI GenInfo Identifier: | 317373338 |
| NCBI Gene ID: | 10666 |
| NCBI Accession: | Q15762.2 |
| UniProt Secondary Accession: | Q15762,B2R818, |
| UniProt Related Accession: | Q15762 |
| Molecular Weight: | |
| NCBI Full Name: | CD226 antigen |
| NCBI Synonym Full Names: | CD226 molecule |
| NCBI Official Symbol: | CD226 |
| NCBI Official Synonym Symbols: | PTA1; DNAM1; DNAM-1; TLiSA1 |
| NCBI Protein Information: | CD226 antigen; adhesion glycoprotein; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen |
| UniProt Protein Name: | CD226 antigen |
| UniProt Synonym Protein Names: | DNAX accessory molecule 1 |
| Protein Family: | CD226 antigen |
| UniProt Gene Name: | CD226 |
| UniProt Entry Name: | CD226_HUMAN |
 | Western blot analysis of extracts of mouse lung, using CD226 antibody (CAB10282) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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