バックグラウンド: | This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Protein Function: | Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. |
NCBI Summary: | This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
UniProt Code: | P41217 |
NCBI GenInfo Identifier: | 311033489 |
NCBI Gene ID: | 4345 |
NCBI Accession: | P41217.4 |
UniProt Secondary Accession: | P41217,Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3, B3KQI1, B4DLW9 D3DN65, |
UniProt Related Accession: | P41217 |
Molecular Weight: | 32,975 Da |
NCBI Full Name: | OX-2 membrane glycoprotein |
NCBI Synonym Full Names: | CD200 molecule |
NCBI Official Symbol: | CD200 |
NCBI Official Synonym Symbols: | MRC; MOX1; MOX2; OX-2 |
NCBI Protein Information: | OX-2 membrane glycoprotein |
UniProt Protein Name: | OX-2 membrane glycoprotein |
UniProt Synonym Protein Names: | CD_antigen: CD200 |
UniProt Gene Name: | CD200 |