Anti-CD20 Antibody (RACO0031)
- SKU:
- RACO0031
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- ELISA
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 商品名: | CD20 Antibody |
| Product SKU: | RACO0031 |
| サイズ: | 50ul |
| 宿主種: | Human |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | A synthesized peptide |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | Affinity-chromatography |
| 抗体のクローン性: | Monoclonal |
| アイソタイプ: | Rabbit IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | This protein may be involved in the regulation of B-cell activation and proliferation. |
| シノニム: | B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20 |
| UniProt Protein Function: | MS4A1: This protein may be involved in the regulation of B-cell activation and proliferation. Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5); also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. Belongs to the MS4A family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell surface; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11q12 Cellular Component: extracellular space; integral to plasma membrane; external side of plasma membrane Molecular Function:epidermal growth factor receptor binding Biological Process: B cell proliferation; humoral immune response Disease: Immunodeficiency, Common Variable, 5 |
| NCBI Summary: | This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P11836 |
| NCBI GenInfo Identifier: | 115968 |
| NCBI Gene ID: | 931 |
| NCBI Accession: | P11836.1 |
| UniProt Related Accession: | P11836 |
| Molecular Weight: | |
| NCBI Full Name: | B-lymphocyte antigen CD20 |
| NCBI Synonym Full Names: | membrane spanning 4-domains A1 |
| NCBI Official Symbol: | MS4A1 |
| NCBI Official Synonym Symbols: | B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16 |
| NCBI Protein Information: | B-lymphocyte antigen CD20 |
| UniProt Protein Name: | B-lymphocyte antigen CD20 |
| UniProt Synonym Protein Names: | B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD_antigen: CD20 |
| Protein Family: | CD209 antigen |
| UniProt Gene Name: | MS4A1 |
| UniProt Entry Name: | CD20_HUMAN |