Anti-CD1A Antibody (CAB5722)
- SKU:
- CAB5722
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-CD1A Antibody |
| 抗体コード: | CAB5722 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-181 of human CD1A (NP_001754.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T, HepG2, BT-474 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-181 of human CD1A (NP_001754.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LKEP LSFH VTWI ASFY NHSW KQNL VSGW LSDL QTHT WDSN SSTI VFLC PWSR GNFS NEEW KELE TLFR IRTI RSFE GIRR YAHE LQFE YPFE IQVT GGCE LHSG KVSG SFLQ LAYQ GSDF VSFQ NNSW LPYP VAGN MAKH FCKV LNQN QHEN DITH NLLS D |
| 遺伝子ID: | 909 |
| Uniprot: | P06126 |
| セルラーロケーション: | Cell membrane, Endosome membrane, Single-pass type I membrane protein |
| 計算された分子量: | 37kDa |
| 観察された分子量: | 65kDa |
| 同義語: | CD1A, CD1, FCB6, HTA1, R4, T6 |
| バックグラウンド: | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. |
| NCBI Summary: | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
| UniProt Code: | P06126 |
| NCBI GenInfo Identifier: | 288558852 |
| NCBI Gene ID: | 909 |
| NCBI Accession: | P06126.4 |
| UniProt Related Accession: | P06126 |
| Molecular Weight: | |
| NCBI Full Name: | T-cell surface glycoprotein CD1a |
| NCBI Synonym Full Names: | CD1a molecule |
| NCBI Official Symbol: | CD1A |
| NCBI Official Synonym Symbols: | R4; T6; CD1; FCB6; HTA1 |
| NCBI Protein Information: | T-cell surface glycoprotein CD1a |
| UniProt Protein Name: | T-cell surface glycoprotein CD1a |
| UniProt Synonym Protein Names: | T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; CD_antigen: CD1a |
| Protein Family: | CD109 antigen |
| UniProt Gene Name: | CD1A |
 | Western blot analysis of extracts of various cell lines, using CD1A antibody (CAB5722) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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