Anti-CCT6A Antibody (CAB3589)
- SKU:
- CAB3589
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CCT6A Antibody |
| 抗体コード: | CAB3589 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-250 of human CCT6A (NP_001753.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | BT-474, U-251MG, HeLa, SKOV3, Mouse kidney, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-250 of human CCT6A (NP_001753.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VATA QDDI TGDG TTSN VLII GELL KQAD LYIS EGLH PRII TEGF EAAK EKAL QFLE EVKV SREM DRET LIDV ARTS LRTK VHAE LADV LTEA VVDS ILAI KKQD EPID LFMI EIME MKHK SETD TSLI RGLV LDHG ARHP DMKK RVED AYIL TCNV SLEY EKTE VNSG FFY |
| 遺伝子ID: | 908 |
| Uniprot: | P40227 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 53kDa/58kDa |
| 観察された分子量: | 58kDa |
| 同義語: | CCT6A, CCT-zeta, CCT-zeta-1, CCT6, Cctz, HTR3, MoDP-2, TCP-1-zeta, TCP20, TCPZ, TTCP20 |
| バックグラウンド: | The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. |
| UniProt Protein Function: | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. |
| NCBI Summary: | The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010] |
| UniProt Code: | P40227 |
| NCBI GenInfo Identifier: | 58331171 |
| NCBI Gene ID: | 908 |
| NCBI Accession: | NP_001009186.1 |
| UniProt Secondary Accession: | P40227,Q3KP28, Q75LP4, Q96S46, A6NCD2, |
| UniProt Related Accession: | P40227 |
| Molecular Weight: | 53,289 Da |
| NCBI Full Name: | T-complex protein 1 subunit zeta isoform b |
| NCBI Synonym Full Names: | chaperonin containing TCP1 subunit 6A |
| NCBI Official Symbol: | CCT6A |
| NCBI Official Synonym Symbols: | CCT6; Cctz; HTR3; TCPZ; TCP20; MoDP-2; TTCP20; CCT-zeta; CCT-zeta-1; TCP-1-zeta |
| NCBI Protein Information: | T-complex protein 1 subunit zeta |
| UniProt Protein Name: | T-complex protein 1 subunit zeta |
| UniProt Synonym Protein Names: | Acute morphine dependence-related protein 2; CCT-zeta-1; HTR3; Tcp20 |
| Protein Family: | T-complex protein |
| UniProt Gene Name: | CCT6A |
 | Western blot analysis of extracts of various cell lines, using CCT6A antibody (CAB3589) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human stomach using CCT6A antibody (CAB3589) at dilution of 1:100 (40x lens). |