Anti-CCL27 Antibody (CAB9864)
- SKU:
- CAB9864
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CCL27 Antibody |
| 抗体コード: | CAB9864 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-112 of human CCL27 (NP_006655.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | SKOV3, SW620, Mouse thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-112 of human CCL27 (NP_006655.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FLLP PSTA CCTQ LYRK PLSD KLLR KVIQ VELQ EADG DCHL QAFV LHLA QRSI CIHP QNPS LSQW FEHQ ERKL HGTL PKLN FGML RKMG |
| 遺伝子ID: | 10850 |
| Uniprot: | Q9Y4X3 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 12kDa |
| 観察された分子量: | 16kDa |
| 同義語: | CCL27, ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27 |
| バックグラウンド: | This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. |
| UniProt Protein Function: | CCL27: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10. Belongs to the intercrine beta (chemokine CC) family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Chemokine Chromosomal Location of Human Ortholog: 9p13 Cellular Component: extracellular space; extracellular region Molecular Function:chemokine activity Biological Process: cell-cell signaling; immune response; chemotaxis |
| NCBI Summary: | This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014] |
| UniProt Code: | Q9Y4X3 |
| NCBI GenInfo Identifier: | 7674366 |
| NCBI Gene ID: | 10850 |
| NCBI Accession: | Q9Y4X3.1 |
| UniProt Related Accession: | Q9Y4X3 |
| Molecular Weight: | 12,618 Da |
| NCBI Full Name: | C-C motif chemokine 27 |
| NCBI Synonym Full Names: | chemokine (C-C motif) ligand 27 |
| NCBI Official Symbol: | CCL27 |
| NCBI Official Synonym Symbols: | ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27 |
| NCBI Protein Information: | C-C motif chemokine 27; skinkine; CC chemokine ILC; IL-11 Ralpha-locus chemokine; small-inducible cytokine A27; IL-11 R-alpha-locus chemokine; cutaneous T-cell attracting chemokine; cutaneous T-cell-attracting chemokine; small inducible cytokine subfamily A (Cys-Cys), member 27 |
| UniProt Protein Name: | C-C motif chemokine 27 |
| UniProt Synonym Protein Names: | CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27 |
| Protein Family: | C-C motif chemokine |
| UniProt Gene Name: | CCL27 |
| UniProt Entry Name: | CCL27_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CCL27 antibody (CAB9864) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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