Anti-CCL22 Antibody (CAB1966)
- SKU:
- CAB1966
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CCL22 Antibody |
| 抗体コード: | CAB1966 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IHC |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human CCL22 (NP_002981.2). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:100 |
| 反応性: | Human, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human CCL22 (NP_002981.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MDRL QTAL LVVL VLLA VALQ ATEA GPYG ANME DSVC CRDY VRYR LPLR VVKH FYWT SDSC PRPG VVLL TFRD KEIC ADPR VPWV KMIL NKLS Q |
| 遺伝子ID: | 6367 |
| Uniprot: | O00626 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 10kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | CCL22, A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1 |
| バックグラウンド: | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. |
| UniProt Protein Function: | CCL22: May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. Belongs to the intercrine beta (chemokine CC) family. |
| UniProt Protein Details: | Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide; Chemokine Chromosomal Location of Human Ortholog: 16q13 Cellular Component: extracellular space; extracellular region Molecular Function:chemokine activity Biological Process: cell-cell signaling; response to virus; immune response; chemotaxis; inflammatory response; signal transduction |
| NCBI Summary: | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014] |
| UniProt Code: | O00626 |
| NCBI GenInfo Identifier: | 311033357 |
| NCBI Gene ID: | 6367 |
| NCBI Accession: | O00626.2 |
| UniProt Secondary Accession: | O00626,A0N0Q6, B2R4W2, |
| UniProt Related Accession: | O00626 |
| Molecular Weight: | 10,625 Da |
| NCBI Full Name: | C-C motif chemokine 22 |
| NCBI Synonym Full Names: | chemokine (C-C motif) ligand 22 |
| NCBI Official Symbol: | CCL22 |
| NCBI Official Synonym Symbols: | MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1 |
| NCBI Protein Information: | C-C motif chemokine 22; MDC(1-69); CC chemokine STCP-1; macrophage-derived chemokine; small inducible cytokine A22; small-inducible cytokine A22; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1; small inducible cytokine subfamily A (Cys-Cys), member 22 |
| UniProt Protein Name: | C-C motif chemokine 22 |
| UniProt Synonym Protein Names: | CC chemokine STCP-1; MDC(1-69); Macrophage-derived chemokine; Small-inducible cytokine A22; Stimulated T-cell chemotactic protein 1Cleaved into the following 3 chains:MDC(3-69); MDC(5-69); MDC(7-69) |
| UniProt Gene Name: | CCL22 |
| UniProt Entry Name: | CCL22_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat kidney using CCL22 antibody (CAB1966) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human colon using CCL22 antibody (CAB1966) at dilution of 1:100 (40x lens). |
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