Anti-CCL17 Antibody (CAB2854)
- SKU:
- CAB2854
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CCL17 Antibody |
抗体コード: | CAB2854 |
抗体サイズ: | 20µL, 50µL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant protein of human CCL17 |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Raji, SW620, Mouse thymus, Mouse intestine |
免疫原: | Recombinant protein of human CCL17 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 6361 |
Uniprot: | Q92583 |
セルラーロケーション: | Secreted |
計算された分子量: | 10kDa |
観察された分子量: | 12kDa |
同義語: | CCL17, A-152E5.3, ABCD-2, SCYA17, TARC |
バックグラウンド: | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. |
UniProt Protein Function: | CCL17: Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. Belongs to the intercrine beta (chemokine CC) family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 16q13 Cellular Component: extracellular space; extracellular region Molecular Function:CCR4 chemokine receptor binding; chemokine activity; receptor binding Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; multicellular organismal development; immune response; chemotaxis; inflammatory response; negative regulation of myoblast differentiation |
NCBI Summary: | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014] |
UniProt Code: | Q92583 |
NCBI GenInfo Identifier: | 3024711 |
NCBI Gene ID: | 6361 |
NCBI Accession: | Q92583.1 |
UniProt Secondary Accession: | Q92583,Q2M287, A0N0Q9, |
UniProt Related Accession: | Q92583 |
Molecular Weight: | 10,507 Da |
NCBI Full Name: | C-C motif chemokine 17 |
NCBI Synonym Full Names: | chemokine (C-C motif) ligand 17 |
NCBI Official Symbol: | CCL17 |
NCBI Official Synonym Symbols: | TARC; ABCD-2; SCYA17; A-152E5.3 |
NCBI Protein Information: | C-C motif chemokine 17; CC chemokine TARC; T cell-directed CC chemokine; small-inducible cytokine A17; thymus and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 17 |
UniProt Protein Name: | C-C motif chemokine 17 |
UniProt Synonym Protein Names: | CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine |
UniProt Gene Name: | CCL17 |
UniProt Entry Name: | CCL17_HUMAN |
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