Anti-CBX8 Antibody (CAB6222)
- SKU:
- CAB6222
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-CBX8 Antibody |
抗体コード: | CAB6222 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human CBX8 (NP_065700.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | A-549, 293T, HeLa, MCF-7, Mouse thymus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human CBX8 (NP_065700.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LLKA QAKA KAKT YEFR SDSA RGIR IPYP GRSP QDLA STSR AREG LRNM GLSP PASS TSTS STCR AEAP RDRD RDRD RDRE RDRE RERE RERE RERE RERE RGTS RVDD KPSS PGDS SKKR GPKP RKEL PDPS QRPL GEPS AGLG EYLK GRKL DDTP SGAG KFPA GHSV IQLA RRQD SDLV QCGV TSPS SAEA TGKL AVDT F |
遺伝子ID: | 57332 |
Uniprot: | Q9HC52 |
セルラーロケーション: | Nucleus |
計算された分子量: | 43kDa |
観察された分子量: | 50kDa |
同義語: | CBX8, PC3, RC1 |
バックグラウンド: |
UniProt Protein Function: | CBX8: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: nucleoplasm; heterochromatin; nuclear chromatin; PcG protein complex; nucleus Molecular Function:protein binding; single-stranded RNA binding; ubiquitin-protein ligase activity; methylated histone residue binding Biological Process: transcription, DNA-dependent; histone ubiquitination; negative regulation of transcription from RNA polymerase II promoter |
UniProt Code: | Q9HC52 |
NCBI GenInfo Identifier: | 78099843 |
NCBI Gene ID: | 57332 |
NCBI Accession: | Q9HC52.3 |
UniProt Secondary Accession: | Q9HC52,Q96H39, Q9NR07, |
UniProt Related Accession: | Q9HC52 |
Molecular Weight: | 389 |
NCBI Full Name: | Chromobox protein homolog 8 |
NCBI Synonym Full Names: | chromobox homolog 8 |
NCBI Official Symbol: | CBX8 |
NCBI Official Synonym Symbols: | PC3; RC1 |
NCBI Protein Information: | chromobox protein homolog 8; polycomb 3; rectachrome 1; Pc class 3 homolog; chromobox homolog 8 (Pc class homolog, Drosophila) |
UniProt Protein Name: | Chromobox protein homolog 8 |
UniProt Synonym Protein Names: | Polycomb 3 homolog; Pc3; hPc3; Rectachrome 1 |
Protein Family: | Chromobox protein |
UniProt Gene Name: | CBX8 |
UniProt Entry Name: | CBX8_HUMAN |
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