Anti-CAPZA2 Antibody (CAB2054)
- SKU:
- CAB2054
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CAPZA2 Antibody |
| 抗体コード: | CAB2054 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA2 (NP_006127.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, THP-1, 22Rv1, Mouse brain, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA2 (NP_006127.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MADL EEQL SDEE KVRI AAKF IIHA PPGE FNEV FNDV RLLL NNDN LLRE GAAH AFAQ YNLD QFTP VKIE GYED QVLI TEHG DLGN GKFL DPKN RICF KFDH LRKE ATDP RPCE VENA VESW RTSV ETAL RAYV KEHY PNGV CTVY GKKI DGQQ TIIA CIES HQFQ AKNF WNGR WRSE WKFT ITPS TTQV VGIL KIQV HYYE DGNV QLVS HKDI QDSL TVSN EVQT AKEF IKIV EAAE NEYQ TAIS ENYQ TMSD TTFK ALRR QLPV TRTK IDWN KILS YKIG KEMQ NA |
| 遺伝子ID: | 830 |
| Uniprot: | P47755 |
| セルラーロケーション: | |
| 計算された分子量: | 19kDa/32kDa |
| 観察された分子量: | 38kDa |
| 同義語: | CAPZA2, CAPPA2, CAPZ |
| バックグラウンド: | The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. |
| UniProt Protein Function: | CAPZA2: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Belongs to the F-actin-capping protein alpha subunit family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 7q31.2-q31.3 Cellular Component: cortical cytoskeleton; F-actin capping protein complex; membrane; extracellular region; cytosol; actin cytoskeleton Molecular Function:actin binding Biological Process: innate immune response; protein complex assembly; cell motility; barbed-end actin filament capping; blood coagulation |
| NCBI Summary: | The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P47755 |
| NCBI GenInfo Identifier: | 1345695 |
| NCBI Gene ID: | 830 |
| NCBI Accession: | P47755.3 |
| UniProt Secondary Accession: | P47755,B4DG50, |
| UniProt Related Accession: | P47755 |
| Molecular Weight: | 286 |
| NCBI Full Name: | F-actin-capping protein subunit alpha-2 |
| NCBI Synonym Full Names: | capping protein (actin filament) muscle Z-line, alpha 2 |
| NCBI Official Symbol: | CAPZA2 |
| NCBI Official Synonym Symbols: | CAPZ; CAPPA2 |
| NCBI Protein Information: | F-actin-capping protein subunit alpha-2; capZ alpha-2; F-actin capping protein alpha-2 subunit |
| UniProt Protein Name: | F-actin-capping protein subunit alpha-2 |
| UniProt Synonym Protein Names: | CapZ alpha-2 |
| Protein Family: | F-actin-capping protein |
| UniProt Gene Name: | CAPZA2 |
| UniProt Entry Name: | CAZA2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CAPZA2 antibody (CAB2054) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunohistochemistry of paraffin-embedded Human colon using CAPZA2 Rabbit pAb (CAB2054) at dilution of 1:50 (40x lens). |
 | Immunohistochemistry of paraffin-embedded Mouse kidney using CAPZA2 Rabbit pAb (CAB2054) at dilution of 1:50 (40x lens). |
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