Anti-CAPRIN2 Antibody (CAB17365)
- SKU:
- CAB17365
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| 抗体名: | Anti-CAPRIN2 Antibody |
| 抗体コード: | CAB17365 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human CAPRIN2. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | SH-SY5Y, 293T, C6 |
| 免疫原: | Recombinant protein of human CAPRIN2. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 65981 |
| Uniprot: | Q6IMN6 |
| セルラーロケーション: | |
| 計算された分子量: | 126kDa |
| 観察された分子量: | 126kDa |
| 同義語: | EEG1, EEG-1, C1QDC1, RNG140, CAPRIN2 |
| バックグラウンド: | The protein encoded by this gene may regulate the transport of mRNA. It may play a role in the differentiation of erythroblasts. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | C1QDC1: May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. Belongs to the caprin family. 9 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 12p11 Cellular Component: nucleoplasm; centrosome; mitochondrion; cytoplasm; nucleus; receptor complex Molecular Function:protein binding; RNA binding; receptor binding Biological Process: positive regulation of protein binding; negative regulation of translation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of cell growth; positive regulation of dendrite morphogenesis; positive regulation of peptidyl-serine phosphorylation |
| NCBI Summary: | The protein encoded by this gene may be involved in the transitioning of erythroblasts from a highly proliferative state to a terminal phase of differentiation. High level expression of the encoded protein can lead to apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] |
| UniProt Code: | Q6IMN6 |
| NCBI GenInfo Identifier: | 74748798 |
| NCBI Gene ID: | 65981 |
| NCBI Accession: | Q6IMN6.1 |
| UniProt Secondary Accession: | Q6IMN6,Q149P6, Q149P7, Q6IMN5, Q7Z371, Q8TE70, Q8TE71 Q96RN6, Q9H667, Q9HAL4, E4NKG2, |
| UniProt Related Accession: | Q6IMN6 |
| Molecular Weight: | 101,929 Da |
| NCBI Full Name: | Caprin-2 |
| NCBI Synonym Full Names: | caprin family member 2 |
| NCBI Official Symbol: | CAPRIN2 |
| NCBI Official Synonym Symbols: | EEG1; EEG-1; C1QDC1; RNG140 |
| NCBI Protein Information: | caprin-2; RNA granule protein 140; C1q domain-containing protein 1; gastric cancer multidrug resistance-associated protein; cytoplasmic activation/proliferation-associated protein 2 |
| UniProt Protein Name: | Caprin-2 |
| UniProt Synonym Protein Names: | C1q domain-containing protein 1; Cytoplasmic activation/proliferation-associated protein 2; Gastric cancer multidrug resistance-associated protein; Protein EEG-1; RNA granule protein 140 |
| Protein Family: | Caprin |
| UniProt Gene Name: | CAPRIN2 |
| UniProt Entry Name: | CAPR2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CAPRIN2 antibody (CAB17365) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 3min. |
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