Anti-CAPG Antibody (CAB4413)

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SKU:
CAB4413
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
AFCP
Synonyms:
HEL-S-66
Synonyms:
MCP
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Description

I抗体名:CAPG Rabbit mAb
抗体コード:CAB4413
サイズ:20uL, 50uL, 100uL
同義語:AFCP, HEL-S-66, MCP
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:A synthesized peptide derived from human CAPG
申し込み:WB
推奨される希釈:WB 1:500 - 1:2000
反応性:Human, Mouse, Rat
ポジティブサンプル:HeLa, Mouse lung, Mouse spleen, Mouse kidney, Rat lung
免疫原:A synthesized peptide derived from human CAPG
精製方法:Affinity purification
保管所:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:822
Uniprot:P40121
計算された分子量:38kDa
観察された分子量:38KDa
UniProt Protein Function:CAPG: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Belongs to the villin/gelsolin family.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: F-actin capping protein complex; melanosome; nucleus

Molecular Function:actin binding

Biological Process: protein complex assembly; cell projection biogenesis; barbed-end actin filament capping

NCBI Summary:This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]
UniProt Code:P40121
NCBI GenInfo Identifier:313104088
NCBI Gene ID:822
NCBI Accession:P40121.2
UniProt Secondary Accession:P40121,Q53SA7, B8ZZS7, D6W5K8,
UniProt Related Accession:P40121
Molecular Weight:348
NCBI Full Name:Macrophage-capping protein
NCBI Synonym Full Names:capping protein (actin filament), gelsolin-like
NCBI Official Symbol:CAPG  
NCBI Official Synonym Symbols:MCP; AFCP; HEL-S-66  
NCBI Protein Information:macrophage-capping protein; macrophage capping protein; gelsolin-like capping protein; actin regulatory protein CAP-G; actin-regulatory protein CAP-G; epididymis secretory protein Li 66
UniProt Protein Name:Macrophage-capping protein
UniProt Synonym Protein Names:Actin regulatory protein CAP-G
Protein Family:Protein
UniProt Gene Name:CAPG  
UniProt Entry Name:CAPG_HUMAN
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