Anti-CAP1 Antibody (CAB14577)
- SKU:
- CAB14577
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CAP1 Antibody |
| 抗体コード: | CAB14577 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CAP1 (NP_006358.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, 293T, A-431, HepG2, Rat thymus, Mouse thymus |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CAP1 (NP_006358.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MADM QNLV ERLE RAVG RLEA VSHT SDMH RGYA DSPS KAGA APYV QAFD SLLA GPVA EYLK ISKE IGGD VQKH AEMV HTGL KLER ALLV TASQ CQQP AENK |
| 遺伝子ID: | 10487 |
| Uniprot: | Q01518 |
| セルラーロケーション: | Cell membrane, Peripheral membrane protein |
| 計算された分子量: | 51kDa |
| 観察された分子量: | 60kDa |
| 同義語: | CAP1, CAP, CAP1-PEN |
| バックグラウンド: | The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| UniProt Protein Function: | CAP1: an actin binding protein. Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity. |
| UniProt Protein Details: | Protein type:Actin-binding; Cytoskeletal Chromosomal Location of Human Ortholog: 1p34.2 Cellular Component: cortical actin cytoskeleton; focal adhesion; plasma membrane Molecular Function:actin binding Biological Process: axon guidance; platelet activation; receptor-mediated endocytosis; platelet degranulation; ameboidal cell migration; adenylate cyclase activation; establishment and/or maintenance of cell polarity; signal transduction; blood coagulation; actin cytoskeleton organization and biogenesis |
| NCBI Summary: | The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q01518 |
| NCBI GenInfo Identifier: | 308153681 |
| NCBI Gene ID: | 10487 |
| NCBI Accession: | Q01518.5 |
| UniProt Secondary Accession: | Q01518,P40124, Q08163, |
| UniProt Related Accession: | Q01518 |
| Molecular Weight: | 475 |
| NCBI Full Name: | Adenylyl cyclase-associated protein 1 |
| NCBI Synonym Full Names: | CAP, adenylate cyclase-associated protein 1 (yeast) |
| NCBI Official Symbol: | CAP1 |
| NCBI Official Synonym Symbols: | CAP; CAP1-PEN |
| NCBI Protein Information: | adenylyl cyclase-associated protein 1; CAP 1 |
| UniProt Protein Name: | Adenylyl cyclase-associated protein 1 |
| Protein Family: | CAP1-binding-protein |
| UniProt Gene Name: | CAP1 |
| UniProt Entry Name: | CAP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CAP1 antibody (CAB14577) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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