Anti-Calcineurin A Antibody (CAB4346)
- SKU:
- CAB4346
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
抗体名: | Anti-Calcineurin A Antibody |
抗体コード: | CAB4346 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human Calcineurin A |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | MCF7, U-937, C6, SH-SY5Y, Mouse brain, Rat brain |
免疫原: | A synthesized peptide derived from human Calcineurin A |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 5530 |
Uniprot: | Q08209 |
セルラーロケーション: | |
計算された分子量: | 59kDa |
観察された分子量: | 59KDa |
同義語: | CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B |
バックグラウンド: |
UniProt Protein Function: | PPP3CA: a calmodulin-dependent Ser/Thr phosphatase also known calcineurin A alpha. Involved in a wide range of biologic activities, acting as a Ca(2 )-dependent modifier of phosphorylation status. Dephosphorylates HSPB1. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively.. |
UniProt Protein Details: | Protein type:Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16 Chromosomal Location of Human Ortholog: 4q24 Cellular Component: nucleoplasm; mitochondrion; cytoplasm; Z disc; cytosol; calcineurin complex; sarcolemma Molecular Function:calmodulin binding; protein dimerization activity; protein binding; enzyme binding; calmodulin-dependent protein phosphatase activity; protein heterodimerization activity; protein serine/threonine phosphatase activity; drug binding; calcium ion binding Biological Process: regulation of synaptic transmission; positive regulation of NFAT protein import into nucleus; T cell activation; response to amphetamine; skeletal muscle fiber development; protein amino acid dephosphorylation; negative regulation of insulin secretion; calcineurin-NFAT signaling pathway; transition between fast and slow fiber; dephosphorylation; protein import into nucleus; calcium ion transport; innate immune response; positive regulation of transcription from RNA polymerase II promoter; response to calcium ion; regulation of excitatory postsynaptic membrane potential; multicellular organismal response to stress; G1/S transition of mitotic cell cycle |
UniProt Code: | Q08209 |
NCBI GenInfo Identifier: | 1352673 |
NCBI Gene ID: | 5530 |
NCBI Accession: | Q08209.1 |
UniProt Related Accession: | Q08209 |
Molecular Weight: | 59kDa |
NCBI Full Name: | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform |
NCBI Synonym Full Names: | protein phosphatase 3 catalytic subunit alpha |
NCBI Official Symbol: | PPP3CA |
NCBI Official Synonym Symbols: | CALN; CCN1; CNA1; CALNA; IECEE; PPP2B; ACCIID; CALNA1; IECEE1 |
NCBI Protein Information: | serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform |
UniProt Protein Name: | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform |
UniProt Synonym Protein Names: | CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform |
UniProt Gene Name: | PPP3CA |
UniProt Entry Name: | PP2BA_HUMAN |