Anti-CACNG4 Antibody (CAB14118)
- SKU:
- CAB14118
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CACNG4 Antibody |
| 抗体コード: | CAB14118 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 208-327 of human CACNG4 (NP_055220.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Mouse spinal cord, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 208-327 of human CACNG4 (NP_055220.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | EKNK ELRF KTKR EFLK ASSS SPYA RMPS YRYR RRRS RSSS RSTE ASPS RDVS PMGL KITG AIPM GELS MYTL SREP LKVT TAAS YSPD QEAS FLQV HDFF QQDL KEGF HVSM LNRR TTPV |
| 遺伝子ID: | 27092 |
| Uniprot: | Q9UBN1 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 36kDa |
| 観察された分子量: | 30kDa |
| 同義語: | CACNG4 |
| バックグラウンド: | The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. |
| UniProt Protein Function: | CACNG4: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Channel, calcium Chromosomal Location of Human Ortholog: 17q24 Cellular Component: integral to plasma membrane; plasma membrane; voltage-gated calcium channel complex Molecular Function:channel regulator activity; voltage-gated calcium channel activity Biological Process: membrane depolarization; synaptic transmission; transmission of nerve impulse; transport |
| NCBI Summary: | The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010] |
| UniProt Code: | Q9UBN1 |
| NCBI GenInfo Identifier: | 10719940 |
| NCBI Gene ID: | 27092 |
| NCBI Accession: | Q9UBN1.1 |
| UniProt Secondary Accession: | Q9UBN1,B2RCK0, |
| UniProt Related Accession: | Q9UBN1 |
| Molecular Weight: | 36,579 Da |
| NCBI Full Name: | Voltage-dependent calcium channel gamma-4 subunit |
| NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit gamma 4 |
| NCBI Official Symbol: | CACNG4 |
| NCBI Protein Information: | voltage-dependent calcium channel gamma-4 subunit |
| UniProt Protein Name: | Voltage-dependent calcium channel gamma-4 subunit |
| UniProt Synonym Protein Names: | Neuronal voltage-gated calcium channel gamma-4 subunit; Transmembrane AMPAR regulatory protein gamma-4; TARP gamma-4 |
| Protein Family: | Voltage-dependent calcium channel |
| UniProt Gene Name: | CACNG4 |
| UniProt Entry Name: | CCG4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CACNG4 antibody (CAB14118) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunofluorescence analysis of A549 cells using CACNG4 antibody (CAB14118). Blue: DAPI for nuclear staining. |
View AllClose