Anti-CACNB4 Antibody (CAB9304)
- SKU:
- CAB9304
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CACNB4 Antibody |
抗体コード: | CAB9304 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 401-520 of human CACNB4 (NP_000717.2). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 401-520 of human CACNB4 (NP_000717.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ATHT TSST PMTP LLGR NLGS TALS PYPT AISG LQSQ RMRH SNHS TENS PIER RSLM TSDE NYHN ERAR KSRN RLSS SSQH SRDH YPLV EEDY PDSY QDTY KPHR NRGS PGGY SHDS RHRL |
遺伝子ID: | 785 |
Uniprot: | O00305 |
セルラーロケーション: | |
計算された分子量: | 51kDa/54kDa/56kDa/58kDa |
観察された分子量: | 58kDa |
同義語: | CACNB4, CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6 |
バックグラウンド: | This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. |
NCBI Summary: | This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5. [provided by RefSeq, Aug 2016] |
UniProt Code: | O00305 |
NCBI GenInfo Identifier: | 54607064 |
NCBI Gene ID: | 785 |
NCBI Accession: | NP_000717 |
UniProt Related Accession: | O00305 |
Molecular Weight: | |
NCBI Full Name: | voltage-dependent L-type calcium channel subunit beta-4 isoform b |
NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit beta 4 |
NCBI Official Symbol: | CACNB4 |
NCBI Official Synonym Symbols: | EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4 |
NCBI Protein Information: | voltage-dependent L-type calcium channel subunit beta-4 |
UniProt Protein Name: | Voltage-dependent L-type calcium channel subunit beta-4 |
UniProt Synonym Protein Names: | Calcium channel voltage-dependent subunit beta 4 |
UniProt Gene Name: | CACNB4 |
UniProt Entry Name: | CACB4_HUMAN |
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