Anti-CACNB1 Antibody (CAB7649)
- SKU:
- CAB7649
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CACNB1 Antibody |
抗体コード: | CAB7649 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 429-598 of human CACNB1 (NP_000714.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 429-598 of human CACNB1 (NP_000714.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ATAA LAAS PAPV SNLQ GPYL ASGD QPLE RATG EHAS MHEY PGEL GQPP GLYP SSHP PGRA GTLR ALSR QDTF DADT PGSR NSAY TELG DSCV DMET DPSE GPGL GDPA GGGT PPAR QGSW EDEE EDYE EELT DNRN RGRN KARY CAEG GGPV LGRN KNEL EGWG RGVY IR |
遺伝子ID: | 782 |
Uniprot: | Q02641 |
セルラーロケーション: | Cell membrane, Cytoplasmic side, Peripheral membrane protein, sarcolemma |
計算された分子量: | 53kDa/57kDa/65kDa |
観察された分子量: | 66kDa |
同義語: | CACNB1, CAB1, CACNLB1, CCHLB1 |
バックグラウンド: | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. |
UniProt Protein Function: | CACNB1: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Belongs to the calcium channel beta subunit family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Channel, calcium Chromosomal Location of Human Ortholog: 17q21-q22 Cellular Component: sarcoplasmic reticulum; T-tubule; voltage-gated calcium channel complex Molecular Function:voltage-gated calcium channel activity; high voltage-gated calcium channel activity Biological Process: synaptic transmission; axon guidance; transport; protein targeting to membrane; neuromuscular junction development |
NCBI Summary: | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q02641 |
NCBI GenInfo Identifier: | 20455481 |
NCBI Gene ID: | 782 |
NCBI Accession: | Q02641.3 |
UniProt Related Accession: | Q02641 |
Molecular Weight: | 57kDa |
NCBI Full Name: | Voltage-dependent L-type calcium channel subunit beta-1 |
NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit beta 1 |
NCBI Official Symbol: | CACNB1 |
NCBI Official Synonym Symbols: | CAB1; CCHLB1; CACNLB1 |
NCBI Protein Information: | voltage-dependent L-type calcium channel subunit beta-1 |
UniProt Protein Name: | Voltage-dependent L-type calcium channel subunit beta-1 |
UniProt Synonym Protein Names: | Calcium channel voltage-dependent subunit beta 1 |
Protein Family: | Voltage-dependent L-type calcium channel |
UniProt Gene Name: | CACNB1 |
UniProt Entry Name: | CACB1_HUMAN |
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