Anti-C5AR1 Antibody (CAB16784)
- SKU:
- CAB16784
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-C5AR1 Antibody |
| 抗体コード: | CAB16784 |
| 抗体サイズ: | 20uL, 50 uL |
| 申し込み: | IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human C5AR1 (NP_001727.1). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human C5AR1 (NP_001727.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SFFI FWLP YQVT GIMM SFLE PSSP TFLL LNKL DSLC VSFA YINC CINP IIYV VAGQ GFQG RLRK SLPS LLRN VLTE ESVV RESK SFTR STVD TMAQ KTQA V |
| 遺伝子ID: | 728 |
| Uniprot: | P21730 |
| セルラーロケーション: | |
| 計算された分子量: | 39kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | C5AR1, C5A, C5AR, C5R1, CD88 |
| バックグラウンド: |
| UniProt Protein Function: | C5aR: a family 1 G-protein coupled receptor that stimulates the GTPase activity of Gi2. Receptor for the chemotactic and inflammatory complement factor C5a. Stimulates chemotaxis, granule enzyme release and superoxide anion production. Phosphorylated in response to C5a or after stimulation of cells with phorbol esters. Expressed on monocytes, granulocytes, dendritic cells, astrocytes and microglia. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 19q13.3-q13.4 Cellular Component: cell surface; basolateral plasma membrane; integral to plasma membrane; apical part of cell; cytoplasmic membrane-bound vesicle; plasma membrane Molecular Function:complement component C5a binding; complement component C5a receptor activity; C5a anaphylatoxin receptor activity Biological Process: neutrophil chemotaxis; sensory perception of chemical stimulus; organ regeneration; apoptosis; activation of MAPK activity; response to lipopolysaccharide; cell proliferation in hindbrain; signal transduction; chemotaxis; mRNA transcription from RNA polymerase II promoter; defense response to Gram-positive bacterium; elevation of cytosolic calcium ion concentration; phospholipase C activation; response to peptidoglycan; cellular defense response; immune response; negative regulation of neuron apoptosis; inflammatory response; positive regulation of epithelial cell proliferation |
| UniProt Code: | P21730 |
| NCBI GenInfo Identifier: | 311033355 |
| NCBI Gene ID: | 728 |
| NCBI Accession: | P21730.2 |
| UniProt Related Accession: | P21730 |
| Molecular Weight: | 39,336 Da |
| NCBI Full Name: | C5a anaphylatoxin chemotactic receptor 1 |
| NCBI Synonym Full Names: | complement component 5a receptor 1 |
| NCBI Official Symbol: | C5AR1 |
| NCBI Official Synonym Symbols: | C5A; C5AR; C5R1; CD88 |
| NCBI Protein Information: | C5a anaphylatoxin chemotactic receptor 1; C5a-R; C5a ligand; C5a anaphylatoxin receptor; complement component 5 receptor 1 |
| UniProt Protein Name: | C5a anaphylatoxin chemotactic receptor 1 |
| UniProt Synonym Protein Names: | C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen: CD88 |
| Protein Family: | C5a anaphylatoxin chemotactic receptor |
| UniProt Gene Name: | C5AR1 |
| UniProt Entry Name: | C5AR1_HUMAN |